Genome-wide associations with song variation in a natural population of Drosophila melanogaster

果蝇自然群体中歌曲变异的全基因组关联

• 批准号: NE/H010548/1
• 负责人: Michael Ritchie
• 金额: $ 3.34万
• 依托单位: University of St Andrews
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2010
• 资助国家: 英国
• 起止时间: 2010 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=NE%2FH010548%2F1
• 关键词: Genome; wide; associations; song; variation

192 inbred lines derived from a single natural population of the fruit fly Drosophila melanogaster (the Drosophila Genetic Reference Panel, DGRP) will have their courtship song recorded and analysed. The design will allow us to measure a range of song parameters, plus collect data on singing rates and mating success. The DGRP lines are part of a coordinated effort by the Drosophila community and are having their genomes sequenced to a high level of coverage. This will allow genome-wide association analyses to be completed for variation in song, and covariation analyses between song and other phenotypes, including mating success. This will provide an unparalleled data set for the analysis of genome-wide associations for variation in important behavioural phenotypes within a single population. Results will be relevant to behaviour genetics, sexual selection and our understanding of the ecological and evolutionary genetics of natural populations.

来自果蝇黑腹果蝇（Drosophila melanogaster）单一自然种群的192个近交系（Drosophila Genetic Reference Panel，DGRP）将记录和分析它们的求偶歌。这个设计将允许我们测量一系列的歌曲参数，并收集关于唱歌率和交配成功率的数据。DGRP系是果蝇社区协调努力的一部分，正在对它们的基因组进行高覆盖率的测序。这将允许完成全基因组关联分析的歌曲，歌曲和其他表型，包括交配成功之间的协变分析的变化。这将提供一个无与伦比的数据集，用于分析单一人群中重要行为表型变异的全基因组关联。研究结果将与行为遗传学、性选择以及我们对自然种群的生态和进化遗传学的理解有关。

项目成果

Postmating-prezygotic isolation between two allopatric populations of Drosophila montana: fertilisation success differs under sperm competition.

• DOI: 10.1002/ece3.1995
• 发表时间: 2016-03
• 期刊: Ecology and evolution
• 影响因子: 2.6
• 作者: Ala-Honkola O;Ritchie MG;Veltsos P
• 通讯作者: Veltsos P