(ENVIRON) Quantifying particle number and specific surface area (SSA) of manufactured nanoparticles

(ENVIRON) 量化制造的纳米颗粒的颗粒数量和比表面积 (SSA)

• 批准号: NE/H018514/1
• 负责人: Jamie Lead
• 金额: $ 9.2万
• 依托单位: University of Birmingham
• 依托单位国家: 英国
• 项目类别: Training Grant
• 财政年份: 2010
• 资助国家: 英国
• 起止时间: 2010 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=NE%2FH018514%2F1
• 关键词: ENVIRON; Quantifying; particle; number; specific

Nanoscience and nanotechnology are concerned with the nanoscale which is usually defined as being between 1 and 100 nm in size. The synthesis and use of nanoparticle (NP) and other nanomaterials (NMs) are significant parts of nanotechnology and there are clearly many economic, environmental and social benefits from the use of NMs as detailed in recent reports from Royal Society and Royal Academy of Engineering and the Royal Commission for Environmental Pollution (http://www.nanotec.org.uk/finalReport.htm; http://www.nanotec.org.uk/finalReport.htm) in energy, in healthcare and in other sectors. However, use of NPs, particularly on the vast scale at which is currently occurring and projected for the future, has led to significant concerns about their human and environmental health effects from the reports mentioned and from others such as the EU SCENIHR (http://ec.europa.eu/health/ph_risk/committees/04_scenihr/docs/scenihr_o_012.pdf) and more widely. Ideally, we require full exploitation of the benefits of nanotechnology while ensuring the environment is not adversely affected. Understanding and quantifying the environmental effects of NMs requires understanding the physico-chemical properties of relevant NPs. Of particular relevance for this project, the appropriate metrics for characterising NP concentration (mass, particle number of surface area) has been questioned and it is recognised that the mass concentration used for conventional chemicals may be inappropriate. The appropriate metrics to use in NP studies is an important policy issue; of the 19 Research Objectives (ROs) produced by the UK government (DEFRA's NRCG http://www.defra.gov.uk/environment/nanotech/research/pdf/nanoparticles-riskreport07.pdf), one is: To identify the most appropriate metrics and appropriate methods for the measurement and characterisation of NPs. This proposal is of both scientific and policy/regulatory importance and will seek to define and test some of the appropriate methods to quantify these two metrics. Objectives 1) To perform a comparative study to quantify particle number concentration. 2) To investigate SSA measurement methods for NPs in liquid. 3) To apply number and SSA techniques to NMs in complex media.

纳米科学和纳米技术涉及纳米尺度，通常定义为1至100 nm的尺寸。纳米颗粒（NP）和其他纳米材料（NM）的合成和使用是纳米技术的重要部分，并且显然存在来自NM的使用的许多经济、环境和社会益处，如来自皇家学会和皇家工程学院以及皇家环境污染委员会（http：//www.nanotec.org.uk/finalReport.htm; http：//www.nanotec.org.uk/finalReport.htm）在能源、医疗保健和其他部门中的最近报告中所详述的。然而，纳米颗粒的使用，特别是目前正在发生的和预计未来的大规模使用，已经引起了上述报告和其他报告，如欧盟《国际卫生健康标准》（http：//ec.europa.eu/health/ph_risk/committees/04_scenihr/docs/scenihr_o_012.pdf）以及更广泛的报告对纳米颗粒对人类和环境健康影响的严重关切。理想情况下，我们需要充分利用纳米技术的好处，同时确保环境不会受到不利影响。了解和量化纳米材料的环境影响需要了解相关纳米材料的物理化学性质。与本项目特别相关的是，表征NP浓度（质量、表面积的颗粒数）的适当指标受到质疑，人们认识到用于常规化学品的质量浓度可能不合适。在NP研究中使用的适当指标是一个重要的政策问题;英国政府制定的19个研究目标（RO）（DEFRA的NRCG http：//www.defra.gov.uk/environment/nanotech/research/pdf/nanoparticles-riskreport07.pdf），其中之一是：确定最合适的指标和适当的方法来测量和表征NP。该提案具有科学和政策/监管两方面的重要性，并将寻求定义和测试一些适当的方法来量化这两个指标。目标1）进行比较研究以量化颗粒物数量浓度。2)探讨液体中纳米粒子的比表面散射测量方法。3)将数字和SSA技术应用于复杂介质中的NM。