CORE--DATA ANALYSIS, STATISTICAL SUPPORT, SPECIMAN BANK

此计划项目的核心提供了一组资源、服务、 以及开展构成部分项目所必需的技能。 这些措施包括： 1.协调支持。威利特博士将协调并提供 本计划内实施的项目的总体方向。《核心》 工作人员将为以下方面提供行政协助和秘书支助 各项目之间的联系，并促进他们之间的交流。 2.半定量食物频率问卷分析系统。 这份问卷调查和营养分析系统是 在所有的成分研究中使用，以及在许多其他研究中使用 我们机构内外的调查人员。核心将支持 高级营养师，负责维护和发展 营养分析系统中使用的食物成分数据库 随附调查问卷。 3.统计服务。唐娜·斯皮格曼博士将提供统计数据 支持这项提案中的所有项目。 4.计算和编程设施。核心将提供 所有组件的计算机硬件和软件资源 项目。这个计算机设施也与护士们的 健康研究I和II.核心中包括的一名程序员将安排 在构成部分的项目和其他大型群体之间传输数据 数据库，并支持维护和开发营养素 分析系统，并将实验室分析结果与我们的 用于嵌套病例对照分析的现有流行病学数据。 5.生物标本库。血液，储存在等量血浆中，巴菲 涂层和液氮冷冻箱中的红细胞售价为18,000美元 卫生专业人员跟踪研究的参与者，并将使用 对于项目I、II和单独资助的研究。核心将支持 监测和维护这一宝贵资源以及 样本检索、等分和运送至协作组 实验室。

The Core for this Program Project provides a group of resources, services, and skills that are essential for the conduct of the component projects. These consist of: 1. Coordination and Support. Dr. Willett will coordinate and provide the overall direction for the projects conducted within this Program. The Core staff will provide administrative assistance and secretarial support for the individual projects and facilitate communications among them. 2. The Semi-Quantitative Food Frequency Questionnaire Analysis System. This questionnaire and nutrient analysis system is a basic resource that is used in all of the component studies, as well as by many other investigators within and outside our institution. The Core will support a Senior Dietitian with responsibility for maintaining and developing the food composition database used in the nutrient analysis system that accompanies the questionnaire. 3. Statistical Services. Dr. Donna Spiegelman will provide statistical support for all of the projects within this proposal. 4. Computing and Programming Facilities. The Core will provide the computer hardware and software resources for all of the component Projects. This computer facility is also coordinated with the Nurses' Health Studies I and II. A programmer included in the Core will arrange transfer of data among the component projects and other large cohort databases, and support the maintenance and development of the nutrient analysis system, and integrate the results of laboratory analyses with our existing epidemiology data for nested case-control analyses. 5. Biological Specimen Bank. Bloods, stored in aliquots of plasma, buffy coat, and red cells in liquid nitrogen freezers, are available for 18,000 participants in the Health Professionals Follow-up Study and will be used for Projects I, II, and separately funded research. The core will support the monitoring and maintenance of this valuable resource as well as specimen retrieval, aliquoting, and shipping to collaborating laboratories.