MARK I, RESEARCH IRRADIATOR WITH CESIUM 137 SOURCE
MARK I,使用铯 137 源的研究辐照器
基本信息
- 批准号:2791074
- 负责人:
- 金额:$ 25.06万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1999
- 资助国家:美国
- 起止时间:1999-01-14 至 2000-06-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This application requests funds to purchase a cesium 137 irradiation source to operate within the barrier Animal Care Facility (ACF) at the Parnassus Heights campus of the University of California, San Francisco (UCSF). Parnassus Heights is the major site of teaching, research, and patient care at UCSF. Locating this instrument within the ACF will allow 11 co-investigators working in the areas of immunology, infectious disease, hematopoiesis, and cancer biology whose laboratories are located on the Parnassus campus to perform experiments which are integral to NIH-funded research projects and which involve transferring hematopoietic cells into irradiated mice. Acquisition of a cesium irradiator for the ACF will ensure that these studies are carried out efficiently, safely, and in a manner that follows well-established procedures for conducting working within the controlled environment of a barrier animal care facility. The applicant group has a excellent record of research productivity and a strong history of collaborating with each other. At present, there is no radiation source available for irradiating small animals at the Parnassus campus. Existing procedures are expensive, cumbersome, and inefficient as they involve housing mice at a different site from the investigator s laboratory or transferring animals to another site within San Francisco for radiation, and then transporting them back to the Parnassus campus. The instrument will be housed within the ACF, will add an important new component to the infrastructure of that facility, and will greatly enhance research efforts of UCSF investigators in addition to the applicant group. The application documents strong institutional support for the proposal.
此应用程序申请资金以购买铯137放射源,以便在加州大学旧金山分校帕纳苏斯高地校区的屏障动物保护设施(ACF)内运行。帕纳苏斯高地是加州大学旧金山分校的教学、研究和病人护理的主要场所。将这台仪器放在ACF内,将允许免疫学、传染病、造血和癌症生物学领域的11名合作研究人员进行实验,他们的实验室位于帕纳苏斯校区,这些实验是NIH资助的研究项目的组成部分,涉及将造血细胞转移到受辐射的小鼠体内。为ACF购买铯辐照器将确保高效、安全地进行这些研究,并遵循在屏障动物护理设施的受控环境中进行工作的既定程序。申请者群体在研究生产力方面有着出色的记录,并且有很强的相互合作的历史。目前,帕纳苏斯校区没有可用于照射小动物的放射源。现有的程序昂贵、繁琐且效率低下,因为它们涉及将老鼠安置在与研究人员S实验室不同的地点,或者将动物转移到旧金山的另一个地点进行辐射,然后再将它们运送回帕纳苏斯校园。该仪器将被安置在ACF内,将为该设施的基础设施增加一个重要的新组成部分,并将极大地加强加州大学旧金山分校调查人员以及申请者群体的研究工作。申请书证明了该提案得到了强有力的机构支持。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
KEVIN M. SHANNON其他文献
KEVIN M. SHANNON的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('KEVIN M. SHANNON', 18)}}的其他基金
In Vivo Functional Analysis of Chromosome 7q22 Deletions in Myeloid Malignancies
骨髓恶性肿瘤中染色体 7q22 缺失的体内功能分析
- 批准号:
9924474 - 财政年份:2017
- 资助金额:
$ 25.06万 - 项目类别:
Selectively Targeting Oncogenic NRAS in Cancer
选择性靶向癌症中的致癌 NRAS
- 批准号:
10372214 - 财政年份:2015
- 资助金额:
$ 25.06万 - 项目类别:
Project 3: Efficacy of MEK Inhibition in Juvenile Myelomonocytic Leukemia
项目3:MEK抑制对幼年粒单核细胞白血病的疗效
- 批准号:
8932164 - 财政年份:2015
- 资助金额:
$ 25.06万 - 项目类别:
Selectively Targeting Oncogenic NRAS in Cancer
选择性靶向癌症中的致癌 NRAS
- 批准号:
10209682 - 财政年份:2015
- 资助金额:
$ 25.06万 - 项目类别:
Selectively Targeting Oncogenic NRAS in Cancer
选择性靶向癌症中的致癌 NRAS
- 批准号:
9040123 - 财政年份:2015
- 资助金额:
$ 25.06万 - 项目类别:
Selectively Targeting Oncogenic NRAS in Cancer
选择性靶向癌症中的致癌 NRAS
- 批准号:
10610346 - 财政年份:2015
- 资助金额:
$ 25.06万 - 项目类别: