CORE--CELL IMAGING

核心--细胞成像

• 批准号: 6201040
• 负责人: BRUCE M CARLSON
• 金额: $ 13.26万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-01 至 2000-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6201040
• 关键词: aging; bioimaging /biomedical imaging; biomedical equipment resource; biomedical facility; confocal scanning microscopy; cytology; digital imaging; fluorescence microscopy; image processing; light microscopy; scanning electron microscopy; transmission electron microscopy

The Cellular Imaging Core is designed to enhance the gerontological research capabilities of members of the Nathan Shock Center of Excellence by giving them access to contemporary imaging technologies and working with them to ensure that the appropriate technology is applied to their specific research problems. Specific aims of this Core are to provide not only the facilities and instrumentation, but also technical help and advice, for the acquisition of cellular imagery. Use of this Core will be open to both members of the Center and to investigators outside the Center, who are conducting collaborative studies that focus on problems in aging. The Core is well equipped with instrumentation at both the cell and tissue level, including transmission and scanning electron microscopes, standard light and confocal microscopes, facilities for specimen preparation, and extensive computer back-up for digital imagery. Investigators using this Core will receive technical assistance in using the instrumentation or may actually collaborate with appropriate investigators on aging-related projects. The Cellular Imaging Core will be an integral component of the Cell Biology Laboratories (CBL), a University microscopy core facility located in the Department of Anatomy and Cell Biology. The CBL, which has been in existence for 15 years, is served by a full-time manager and technician paid by various morphology cores of a variety of research programs. It is administered through the Department of Anatomy and Cell Biology. Investigators from all research groups of the Shock Center plan to use the Cellular Imaging Core.

细胞成像核心旨在增强老年学 内森冲击卓越中心成员的研究能力 通过让他们访问当代成像技术并与之合作 它们以确保适当的技术适用于其特定 研究问题。 该核心的具体目的不仅要提供 设施和工具，以及技术帮助和建议， 获取细胞图像。 该核心的使用将向两者开放 中心成员以及中心外的调查人员 进行着专注于衰老问题的协作研究。 核心 在细胞和组织水平上都配备了仪器， 包括传输和扫描电子显微镜，标准光 以及共聚焦显微镜，标本准备的设施以及 广泛的计算机备份用于数字图像。 调查人员使用此 核心将在使用仪器方面获得技术帮助或可能 实际与适当的调查人员合作就与衰老有关 项目。 蜂窝成像核心将是不可或缺的组成部分 细胞生物学实验室（CBL），大学显微镜核心设施 位于解剖学和细胞生物学系。 CBL，具有 已经存在15年了，由专职经理和 由各种研究的各种形态核心支付的技术人员 程序。 它是通过解剖和细胞部管理的 生物学。 来自冲击中心计划的所有研究小组的研究人员 使用细胞成像芯。