CORE--CELL IMAGING

核心--细胞成像

• 批准号: 6201040
• 负责人: BRUCE M CARLSON
• 金额: $ 13.26万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-01 至 2000-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6201040
• 关键词: aging; bioimaging /biomedical imaging; biomedical equipment resource; biomedical facility; confocal scanning microscopy; cytology; digital imaging; fluorescence microscopy; image processing; light microscopy; scanning electron microscopy; transmission electron microscopy

The Cellular Imaging Core is designed to enhance the gerontological research capabilities of members of the Nathan Shock Center of Excellence by giving them access to contemporary imaging technologies and working with them to ensure that the appropriate technology is applied to their specific research problems. Specific aims of this Core are to provide not only the facilities and instrumentation, but also technical help and advice, for the acquisition of cellular imagery. Use of this Core will be open to both members of the Center and to investigators outside the Center, who are conducting collaborative studies that focus on problems in aging. The Core is well equipped with instrumentation at both the cell and tissue level, including transmission and scanning electron microscopes, standard light and confocal microscopes, facilities for specimen preparation, and extensive computer back-up for digital imagery. Investigators using this Core will receive technical assistance in using the instrumentation or may actually collaborate with appropriate investigators on aging-related projects. The Cellular Imaging Core will be an integral component of the Cell Biology Laboratories (CBL), a University microscopy core facility located in the Department of Anatomy and Cell Biology. The CBL, which has been in existence for 15 years, is served by a full-time manager and technician paid by various morphology cores of a variety of research programs. It is administered through the Department of Anatomy and Cell Biology. Investigators from all research groups of the Shock Center plan to use the Cellular Imaging Core.

细胞成像核心旨在增强老年学 内森休克卓越中心成员的研究能力 通过让他们接触当代成像技术并与 他们确保适当的技术应用于他们的具体情况 研究问题。 该核心的具体目标不仅是提供 设施和仪器，还有技术帮助和建议，为 获取细胞图像。 该核心的使用将向双方开放 中心成员和中心外的调查人员，他们是 开展重点关注老龄化问题的合作研究。 核心 配备了细胞和组织水平的仪器， 包括透射电子显微镜、扫描电子显微镜、标准光 和共焦显微镜、标本制备设施，以及 数字图像的广泛计算机备份。 调查人员利用这个 Core 将获得使用仪器的技术援助，或者可能 实际上与衰老相关的适当研究人员合作 项目。 细胞成像核心将成为 细胞生物学实验室 (CBL)，大学显微镜核心设施 位于解剖学和细胞生物学系。 CBL 拥有 已成立 15 年，由一名全职经理服务， 由各种研究的各种形态核心支付的技术人员 程序。 它由解剖学和细胞系管理 生物学。 休克中心计划所有研究小组的研究人员 to use the Cellular Imaging Core.