Adaptive radiations of New World lupins revealed by transcriptome sequencing

转录组测序揭示新大陆羽扇豆的适应性辐射

• 批准号: NE/K004352/1
• 负责人: Dmitry Filatov
• 金额: $ 26.64万
• 依托单位: University of Oxford
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=NE%2FK004352%2F1
• 关键词: Adaptive; radiations; New; World; lupins

Studies of adaptive radiations - groups of closely related species adapted to very different conditions - have yielded important insights into our understanding of evolution ever since the pioneering works of Darwin and Wallace. Rapid recent radiations of species can be used as models allowing us to study general evolutionary processes that were at work during the major adaptive radiations in the history of our planet. The conditions under which adaptive radiations occur are not well understood and generally it is not clear why some groups of organisms are very species-rich, while others consist of only few species despite similar age. Adaptive radiations can form in a very short period of time, e.g. species-rich groups of African cichlids are only few thousand years old and speciation rates in such groups is very high, yet general reasons for such rapid ('explosive') speciation require further investigation. This project is devoted to the analysis of evolutionary genetic processes during multiple rapid radiations in a plant genus Lupinus (Leguminosae), which exhibits some of the highest known rates of net diversification in plants. Exceptional rates of species diversification have been documented for Andean lupins, where 85 species have evolved in the last 1.8 million years. An independent lineage of lupins is actively radiating in North America. Such replicate radiations provide powerful comparative systems to address questions about the evolutionary forces driving episodes of diversification. Detailed evolutionary genetic analysis of replicate rapid radiations has not been undertaken previously.Despite relatively low sequence divergence among recently diverged species of Western New World lupins, the range of life forms (from dwarf annuals and prostrate herbs to small trees), and habitats occupied is striking. This accelerated morphological and ecological diversification suggests that many genes may have been under strong adaptive selection. The aim of the project is to address currently unanswered questions about the types of genes involved in adaptation during adaptive radiations as well as the relative roles of selection at the amino acid level versus regulatory regions. This will involve the comparisons of the patterns of DNA sequence divergence and gene expression between closely related and recently diverged species with divergent life forms and adapted to a range of environments. Genome-wide DNA polymorphism/divergence as well as expression data will be obtained by Solexa/Illumina sequencing of cDNA. This will be done for actively radiating clades of species in the Andes and North America as well as for a set of species outside actively radiating clades for comparison.

自达尔文和华莱士的开创性工作以来，对适应性辐射--一组适应非常不同条件的密切相关的物种--的研究为我们理解进化提供了重要的见解。物种的快速近代辐射可以作为模型，使我们能够研究在我们星球历史上主要适应性辐射期间起作用的一般进化过程。适应性辐射发生的条件尚不清楚，通常也不清楚为什么有些生物群体物种非常丰富，而另一些生物群体尽管年龄相似，但物种却很少。适应性辐射可以在很短的时间内形成，例如物种丰富的非洲慈鲷只有几千年的历史，这些群体的物种形成率非常高，但这种快速（“爆炸性”）物种形成的一般原因需要进一步调查。该项目致力于分析植物属Lupinus（豆科植物）在多次快速辐射期间的进化遗传过程，该植物属表现出一些已知的最高的植物净多样化率。安第斯羽扇豆的物种多样化速度非常快，在过去的180万年里进化了85个物种。一个独立的羽扇豆谱系正在北美积极辐射。这种复制辐射提供了强有力的比较系统，以解决有关驱动多样化事件的进化力量的问题。复制快速辐射的详细进化遗传分析尚未进行previous.Despite相对较低的序列分歧最近分化的物种之间的西部新世界羽扇豆，生活形式的范围（从矮的一年生植物和匍匐草本小树），和栖息地占用是惊人的。这种加速的形态和生态多样性表明，许多基因可能已经在强大的适应性选择。该项目的目的是解决目前尚未回答的问题，在适应性辐射过程中，以及在氨基酸水平与调节区域的选择的相对作用的适应基因的类型。这将涉及DNA序列差异和基因表达模式的比较密切相关的和最近分化的物种不同的生命形式和适应一系列的环境。将通过Solexa/Illumina cDNA测序获得全基因组DNA多态性/趋异以及表达数据。这将在安第斯山脉和北美的物种的活跃辐射分支，以及为一组物种以外的活跃辐射分支进行比较。

项目成果

Pleistocene diversification of unifoliolate-leaved Lupinus (Leguminosae: Papilionoideae) in Florida

• DOI: 10.1111/mec.17232
• 发表时间: 2024-01-11
• 期刊: MOLECULAR ECOLOGY
• 影响因子: 4.9
• 作者: Nevado，Bruno;Atchison，Guy W.;Hughes，Colin E.
• 通讯作者: Hughes，Colin E.

Exploring the genetic and adaptive diversity of a pan-Mediterranean crop wild relative: narrow-leafed lupin.

• DOI: 10.1007/s00122-017-3045-7
• 发表时间: 2018-04
• 期刊: TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik
• 作者: Mousavi-Derazmahalleh M;Bayer PE;Nevado B;Hurgobin B;Filatov D;Kilian A;Kamphuis LG;Singh KB;Berger JD;Hane JK;Edwards D;Erskine W;Nelson MN
• 通讯作者: Nelson MN

Erratum: The Cardamine hirsuta genome offers insight into the evolution of morphological diversity.

• DOI: 10.1038/nplants.2016.189
• 发表时间: 2016-11-07
• 期刊: NATURE PLANTS
• 影响因子: 18
• 作者: Gan, Xiangchao;Hay, Angela;Kwantes, Michiel;Haberer, Georg;Hallab, Asis;Ioio, Raffaele Dello;Hofhuis, Hugo;Pieper, Bjorn;Cartolano, Maria;Neumann, Ulla;Nikolov, Lachezar A;Song, Baoxing;Hajheidari, Mohsen;Briskine, Roman;Kougioumoutzi, Evangelia;Vlad, Daniela;Broholm, Suvi;Hein, Jotun;Meksem, Khalid;Lightfoot, David;Shimizu, Kentaro K;Shimizu-Inatsugi, Rie;Imprialou, Martha;Kudrna, David;Wing, Rod;Sato, Shusei;Huijser, Peter;Filatov, Dmitry;X Mayer, Klaus F;Mott, Richard;Tsiantis, Miltos
• 通讯作者: Tsiantis, Miltos

Lost crops of the Incas: Origins of domestication of the Andean pulse crop tarwi, Lupinus mutabilis

• DOI: 10.3732/ajb.1600171
• 发表时间: 2016-09-01
• 期刊: AMERICAN JOURNAL OF BOTANY
• 影响因子: 3
• 作者: Atchison, Guy W.;Nevado, Bruno;Hughes, Colin E.
• 通讯作者: Hughes, Colin E.

The western Mediterranean region provided the founder population of domesticated narrow-leafed lupin.

• DOI: 10.1007/s00122-018-3171-x
• 发表时间: 2018-12
• 期刊: TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik
• 作者: Mousavi-Derazmahalleh M;Nevado B;Bayer PE;Filatov DA;Hane JK;Edwards D;Erskine W;Nelson MN
• 通讯作者: Nelson MN