STRUCTURE OF HYPERTROPHIC CENTROSOMES IN HUMAN BREAST TUMORS

本课题研究的重点是内膜系统。 (内质网和外周空泡)贾第鞭毛虫，一种非常 原始的单细胞真核生物。这项研究是一个更大的 细胞内和细胞内转运与蛋白质项目 这种有机体中的分选过程。也有人对 利用视频显微镜对贾第鞭毛虫运动系统的研究 可以看到鞭毛和细胞体一样移动。为了这个 我们与NCMIR合作的目的。断层摄影术 在NCMIR对贾第虫进行了重建，按顺序 要了解内质网与细胞周期的关系 外周液泡。获得了几个断层重建图像。 而阿提亚斯博士在1996年12月访问了NCMIR。我们一直在 追踪内质网和外周的轮廓 使用XVOXTRACE的空泡，并已发送完成的重建 敬阿提亚斯医生。

This project is focused on the study of the endomembranes systems (the endoplasmic reticulum and peripheric vacuoles) of Giardia, a very primitive unicellular eukaryote. This study is part of a larger project on the endocytotic and intracellular trafficking and protein sorting processes in this organism. There is also interest in the study of the motor system of Giardia because by videomicroscopy we could see that the flagella moves as well as cell body. For this purpose we have collaborated with the NCMIR. Tomographic reconstructions have been performed on Giardia at the NCMIR in order to see the relationship between the endoplasmic reticulum and peripheric vacuoles. Several tomographc reconstructions were obtained while Dr. Attias visited the NCMIR in December, 1996. We have been tracing the outlines of the endoplasmic reticulum and the peripheric vacuoles using XVOXTRACE and have sent the completed reconstructions to Dr. Attias.