CORE--ELECTRON MICROSCOPY

电子显微镜核心设施（EMCF）是一个研究资源实验室，为来自梅奥诊所基金会临床和基础科学实验室的研究人员提供标本制备、显微镜、摄影和数字成像服务。该设施设备齐全，可提供标准透射（TEM）和扫描（SEM）电子显微镜。该设施还执行x射线探针微量分析和免疫金标程序。与这一核心有关的费用主要是通过在适当的机构支助下重新充值来回收的。

The Electron Microscopy Core Facility (EMCF) is a research resource laboratory providing specimen preparation, microscopy, photography and digital imaging services to investigators from both clinical and basic science laboratories within the Mayo Clinic Foundation. The facility is fully equipped to offer standard transmission (TEM) and scanning (SEM) electron microscopy. The facility also performs X-ray probe microanalysis and immuno-gold labeling procedures. Costs associated with this core are recovered primarily through recharges with modest institutional support. The EMCF is requesting support specifically for the development of new techniques and procedures in electron microscopy for Cancer Center Members. In addition, methods in electron tomography, cryomicroscopy, and novel methods for identification and localization at the ultrastructural level are being incorporated into the available services of the EMCF. Incorporation of these methodologies will enable Cancer Center members to study three-dimensional structural features of cells and molecules at a resolution and preservation that were previously unattainable.