BRAIN IMAGING OF CHILDHOOD ONSET PSYCHIATRIC DISORDERS, ENDOCRINE DISORDERS

儿童期精神疾病、内分泌疾病的脑部成像

• 批准号: 6123586
• 负责人: Jay N. Giedd
• 金额: $ 6.15万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-01 至 2000-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6123586
• 关键词: bioimaging /biomedical imaging; biomedical resource; child (0-11); computers; endocrine gland /system; female; magnetic resonance imaging; male; mental disorders; model design /development; nervous system; nuclear magnetic resonance spectroscopy; statistics /biometry

Cerebral MRI will be used to assess brain anatomy and function in normal volunteers and subjects with a variety of childhood onset psychiatric disorders including attention deficit disorder, autism, congenital adrenal U hyperplasia. childhood-onset schizophrenia. dyslexia, multidimensional impairment syndrome. obsessive compulsive disorder, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infection (PANDAS), stuttering, Sydenham's chorea, and Tourette's Syndrome. Quantitative measures of brain structure and function will be compared across age, gender. and diagnostic groups. Correlations between brain and behavioral measures will be examined for normal and clinical populations.

脑MRI将用于评估脑解剖结构和功能， 正常志愿者和各种儿童期发作的受试者 精神障碍，包括注意力缺陷障碍，自闭症， 先天性肾上腺U增生 儿童期精神分裂症 诵读困难多方面障碍综合征 强迫 疾病，儿科自身免疫性神经精神疾病相关 链球菌感染（PANDAS），口吃，西德纳姆舞蹈病， 和图雷特综合症 大脑结构的定量测量， 功能将在不同年龄、性别之间进行比较。 诊断组。 将研究大脑和行为测量之间的相关性 对于正常和临床人群。