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ANDROGEN STIMULATED PUBERTAL GROWTH--ROLE OF GH AND IGF1

ANDROGEN STIMULATED PUBERTAL GROWTH--ROLE OF GH AND IGF1
雄激素刺激青春期生长——GH 和 IGF1 的作用
批准号：
6115148
负责人：
BRUCE S KEENAN
金额：
$3.42万
依托单位：
UNIVERSITY OF TEXAS MED BR GALVESTON
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6115148
关键词：
adolescence (12-20) blood chemistry child (0-11) child physical development clinical research dihydrotestosterone estradiol hormone regulation /control mechanism hormone therapy human puberty human subject human therapy evaluation hypogonadism insulinlike growth factor male reproductive system disorder chemotherapy somatotropin testosterone

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英文摘要
Analyzes the androgenic and estrogenic effects of testosterone (T) in stimula-ting growth and the production of growth hormone (GH) and IGF1 at puberty. Boys with delayed puberty will be treated either with T or dihydrotestosterone (DHT). Those effects seen with T treatment but not with DHT are attributable to estradiol, whereas the effects of DHT are considered purely androgenic. Para-meters to be followed include height velocity, bone age, spontaneous and stimulated plasma GH, and IGF1.
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PUBERTAL AND PREPUBERTAL GYNECOMASTIA
NEUROTRANSMITTER REGULATION OF GROWTH HORMONE SECRETION
NEUROTRANSMITTER REGULATION OF GROWTH HORMONE SECRETION
PUBERTAL AND PREPUBERTAL GYNECOMASTIA
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