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ANDROGEN STIMULATED PUBERTAL GROWTH--ROLE OF GH AND IGF1

ANDROGEN STIMULATED PUBERTAL GROWTH--ROLE OF GH AND IGF1
雄激素刺激青春期生长——GH 和 IGF1 的作用
批准号：
6276383
负责人：
BRUCE S KEENAN
金额：
$2.69万
依托单位：
UNIVERSITY OF TEXAS MED BR GALVESTON
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6276383
关键词：
adolescence (12-20) blood chemistry child (0-11) child physical development clinical research dihydrotestosterone estradiol hormone regulation /control mechanism hormone therapy human puberty human subject human therapy evaluation hypogonadism insulinlike growth factor male reproductive system disorder chemotherapy somatotropin testosterone

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英文摘要
Analyzes the androgenic and estrogenic effects of testosterone (T) in stimulating growth and the production of growth hormone (GH) and IGF1 at puberty. Boys with delayed puberty will be treated either with T or dihydrotestosterone (DHT). Those effects seen with T treatment but not with DHT are attributable to estradiol, whereas the effects of DHT are considered purely androgenic. Parameters to be followed include height velocity, bone age, spontaneous and stimulated plasma GH, and IGF1.
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PUBERTAL AND PREPUBERTAL GYNECOMASTIA
NEUROTRANSMITTER REGULATION OF GROWTH HORMONE SECRETION
NEUROTRANSMITTER REGULATION OF GROWTH HORMONE SECRETION
PUBERTAL AND PREPUBERTAL GYNECOMASTIA
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