A nanomedicine strategy for detecting and modulating protease activity in vivo
A nanomedicine strategy for detecting and modulating protease activity in vivo
批准号:
nhmrc : 1024723
负责人:
Prof Denis Wakefield
金额:
$30.38万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2015-12-31
中文摘要
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英文摘要
Protease enzymes are vitally important for normal bodily function but can play a deleterious role in many diseases such as cancer, aging diseases and eye diseases. The proposed research will provide a nanomedicine solution to the detection and therapeutic control of protease activity in vivo using nanoporous optical devices that are benign to the body. This general strategy for will be demonstrated in eyes with a view to detection and treating the eye disease uveitis.
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