CORE--ASSESSMENT, CO-MORBIDITY, AND HEALTH SERVICES RESEARCH

评估、科摩罗和卫生服务研究核心将 支持下列干预项目和试点研究： 1）招募和筛选符合条件的患者 参与研究; 2）保留参与研究的受试者 研究; 3）评估受试者是否存在共病 可能影响对《公约》的遵守和反应的情况 干预措施; 4）参与受试者的功能评估 干预研究，包括使用自我报告措施， 基于性能的物理能力测量;以及5）成本分析- 干预措施的有效性和成本效益。 为了实现这些目标，核心有以下具体目标： 建立诊断为间歇性 跛行和充血性心力衰竭; 2）制定和实施 全面的评估方案，包括人口统计学，临床， 社会心理和功能状态测量，用于IS、IDS和 所有试点研究; 3）收集关于保健消费的数据 资源，包括直接和间接的治疗费用， 所用卫生服务的总费用、自付费用和第三方费用， IS、IDS和初步研究所有治疗组的受试者; 5） 为了收集与不同的生活质量结果相关的数据， 6）进行成本效益和成本- 使用公认的方法对干预措施进行效用分析。 评估、科摩罗和卫生服务研究核心还将 提供机会，以加强研究技能的发展， 初级研究人员，包括博士后研究员和初级教员， 和通过研究开发核心确定的研究助理， 包括为有关主题的试点研究项目提供支持 OAIC的活动。 因此，核心将是一个组成部分， 马里兰州大学OAIC通过构建患者 登记研究、合并症数据收集以及功能和健康 成本效益分析的进行和教育 临床流行病学和卫生服务领域的调查人员 research.

The Assessment, Comorbidity and Health Services Research Core will support the intervention projects and pilot studies in the following areas: 1) recruitment and screening of patients eligible for participation in the studies; 2) retention of subjects participating in the studies; 3) assessment of subjects for the presence of comorbid conditions which might influence both compliance with and response to the interventions; 4) functional assessment of subjects participating in the intervention studies including use of self-report measures and performance-based measures of physical capacity; and 5) analysis of cost- effectiveness and cost-utility of the interventions. To accomplish these goals, the Core has the following specific aims: 1) To develop registries of patients with the diagnoses of intermittent claudication and congestive heart failure; 2) To develop and implement a comprehensive assessment protocol including demographic, clinical, psychosocial, and functional status measures for use in the IS, IDS, and all pilot studies; 3) To collect data on the consumption of health care resources, including both direct and indirect costs of treatment and total, out-of-pocket, and third-party costs of health services utilized, by subjects in all treatment arms of the IS, IDS, and pilot studies; 5) To collect data on quality of life outcomes associated with the different arms of the interventions; and 6) To conduct cost-effectiveness and cost- utility analyses of the interventions, using accepted methodology. The Assessment, Comorbidity and Health Services Research Core will also provide opportunities to enhance the development of research skills of junior investigators, including postdoctoral fellows and junior faculty, and research associates identified through the Research Development Core, including providing support for Pilot Research Projects on topics related to the activities of the OAIC. Thus, the Core will be an integral part of the University of Maryland OAIC through the construction of patient registries, collection of data on comorbidities and functional and health status, conduct of cost-effectiveness analyses, and education of investigators in the areas of clinical epidemiology and health services research.