OAI STUDY BALTIMORE CLINICAL CENTER

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。骨关节炎倡议（OAI）是一项多中心观察性队列研究，旨在确定膝关节骨关节炎发生和/或进展的生物标志物。招募对象为45-79岁的男性和女性。有兴趣的当事人将由训练有素的面试官通过电话进行面试。如果认为符合条件，将安排一次筛选访问。如果在筛查访问时获得的x光片符合资格，则会在6周内安排登记访问。每位入组参与者预计将完成四次年度随访临床访问，与入组访问相当。每个临床中心（包括巴尔的摩在内共有4个）预计将招募1250名受试者；对于巴尔的摩，这个数字将在马里兰大学巴尔的摩分校和约翰霍普金斯大学湾景分校之间分配。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Osteoarthritis Initiative (OAI) is a multicenter observational cohort study designed to identify biomarkers for the development and/or progression of osteoarthritis of the knee. Men and women aged 45-79 years of age are targeted for enrollment. Interested parties are interviewed over the telephone by a trained interviewer. If deemed eligible, a screening visit is scheduled. If eligible based on the radiographs obtained at the screening visit, an enrollment visit is scheduled within 6 weeks. Each enrolled participant is expected to complete four annual follow-up clinical visits which are comparable to the enrollment visit. Each clinical center (there are 4, including Baltimore) is expected to recruit 1,250 subjects; for Baltimore, this number will be split between the University of Maryland Baltimore site and the Johns Hopkins Bayview site.