SINGLE CENTER STUDY OF THE PHARMACODYNAMICS OF ALOSETRON IN IBS

阿洛司琼治疗 IBS 的药效学单中心研究

• 批准号: 6117428
• 负责人: M CAMILLERI
• 金额: $ 2.01万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6117428
• 关键词: clinical research; drug screening /evaluation; gastrointestinal absorption /transport; gastrointestinal disorder chemotherapy; human subject; human therapy evaluation; irritable bowel syndrome; pharmacokinetics; rectum /anus; serotonin inhibitor; therapy compliance

This study assesses the effects of a new drug, alosetron, on transit through the digestive tract and on rectal sensation in patients with irritable bowel syndrome over a 12-week period. We have completed this study and wish to close it. This study explored the mechanism of the beneficial clinical effect of alosetron in patients with irritable bowel syndrome. We are still completing data analyses and have not unblinded the investigators. Therefore, no conclusion can be reported here.

这项研究评估了一种新药阿洛司琼对肠易激综合征患者在12周内通过消化道和直肠感觉的影响。我们已经完成了这项研究，并希望关闭它。这项研究探讨了机制的有益的临床效果，阿洛司琼在肠易激综合征患者。 我们仍在完成数据分析，尚未对研究者揭盲。 因此，此处无法报告结论。