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SARCOPENIA: TESTOSTERONE DOSE RESPONSE IN OLDER MEN

SARCOPENIA: TESTOSTERONE DOSE RESPONSE IN OLDER MEN
肌肉减少症：老年男性的睾酮剂量反应
批准号：
6264891
负责人：
RICHARD CASABURI
金额：
$0.1万
依托单位：
LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6264891
关键词：
age difference clinical research dosage hormone metabolism hormone therapy human old age (65+) human subject insulin sensitivity /resistance lipid metabolism male muscle strength protein biosynthesis sex behavior testosterone young adult human (21-34)

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中文摘要
翻译
研究雄激素依赖性生理过程的睾酮剂量依赖性，如蛋白质合成、胰岛素敏感性、无脂肪量、肌肉大小、性功能和血脂。另一个目的是比较年轻男性和老年男性的睾酮剂量反应曲线，以确定老年男性是否对睾酮的合成代谢作用相对不敏感
英文摘要
To examine the testosterone dose-dependency of androgen-dependent physiologic processes such as protein synthesis, insulin sensitivity, fat-free mass, muscle size, sexual function, and plasma lipids. An additional objective is to compare the testosterone dose-response curves in young and older men in order to determine if older men are relatively insensitive to the anabolic effects of testosterone
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