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GAMMA TUBULIN RING COMPLEX STRUCTURE: CENTROMERIC MICROTUBLES:DROSOPHILA EMBRYOS

GAMMA TUBULIN RING COMPLEX STRUCTURE: CENTROMERIC MICROTUBLES:DROSOPHILA EMBRYOS
伽玛微管蛋白环复合体结构:着丝粒微管:果蝇胚胎
批准号:
6120594
负责人:
Yixian Zheng
金额:
$1.18万
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-04-01 至 2000-03-31

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英文摘要
The origin recognition complex (ORQ in yeast is composed of six subunits. They are attemptmg to crystallize it to determme its structure by x-ray crystallography. Meanwhile, they would like to determine the stoichiometry of the complex using-the STEM. Preliminary results have been somewhat encouragmg, in that while the complex seems:to fall apart on the carbon support film, it seems to be fairly well-preserved by a brief glutaraldehyde fixation. Both the ORC alone and the ORC plus DNA will be looked at
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