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, STRUCTURE OF Y TUBULIN RING COMPLEX

, STRUCTURE OF Y TUBULIN RING COMPLEX
, Y 微管蛋白环复合物的结构
批准号：
6281368
负责人：
Yixian Zheng
金额：
$0.32万
依托单位：
BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-04-01 至 1999-03-31
来源：
https://reporter.nih.gov/project-details/6281368
关键词：
animal tissue biomedical resource genome growth /development

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英文摘要
A study of the shucture and function of a microtubule-nucleating complex from Drosophild embryo extracts was initiated. The y-TuRC (y-Tubulin Ring Complex) appeared as disc-shaped particles in the STEM when the specimen was fi=ze-dried, simila to previous TEM image& The preparation was relatively clean and the complexes were approximately 2.5 MDa. Many additional experiments are planned. It turns out that their preparations routinely have 2kDa peptides (to elute the complex from a column) which has'caused bad background problems. Work is underway to avoid this.
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