TESTING OF DENTAL RESTORATIVE MATERIAL

牙科修复材料的测试

• 批准号: 6259253
• 负责人: HENRY L YOUNG
• 金额: $ 0.27万
• 依托单位: MEHARRY MEDICAL COLLEGE
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-01 至 2003-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6259253
• 关键词: biomaterial evaluation; composite resins; dental material wear; dental materials; human subject

The long term goal of the project is to provide clinicians with scientific information which they could use to assist in making the best selection of which restorative material they would incorporate in providing treatment options for patients. Presently, there is an increase in usage of composite resins as posterior restorations. To date most research efforts have been devoted to improving the wear resistance of composite resin restorations. Little effort has been made to determine possible wear of the cusp opposing the composite restoration. The specific aim of this proposed study is to evaluate the effect of a series of five composite in lay systems, of varying composition and particle size, on the wear resistance of human enamel. This project will consist of two phases. Phase I will consist of an in vitro study and Phase II an in vivo study. In Phase I caries free extracted human molars are selected for the study. The specimen is prepared and an composite in lay fabricated and cemented. The specimen is mounted and inserted into a wear test apparatus. This wear device can be used for the critical evaluation of all restorative materials and in fact has been used in conjunction with past studies as well as implants. The teeth selected as the antagonist will consist of the buccal cusp of mandibular first premolars. Small acrylic resin beads are used to serve as the food bolus thereby generating as well as the restored surface of the molar will be evaluated using an image-analyzing system. The surface area for wear facets is calculated automatically by a computer at a magnification of x5O. The values of the surface area for wear facets will be statistically analyzed by a one-factor analysis of variance (P-1 <05). Multiple comparison among respective composite resins will be made with the Fisher test at a 95% level of confidence. In Phase II one hundred composite inlays will be inserted into Class I and II cavity preparations in vivo. All restorations will be inserted over a ninety day period by two clinicians following a strict clinical protocol. The antagonist cusp and the posterior restoration will be evaluated at baseline 3 mos., 6 mos., 12 mos., 24 mos., 36 mos. and 48 mos. By indirect evaluation using epoxy resin models, the wear of the opposing cusp as well as the composite restoration will be determined using an image analyzing system. The same protocol for analysis of data used in Phase l will be repeated for Phase Il.

该项目的长期目标是为临床医生提供科学的 他们可以用来帮助做出最佳选择的信息 他们在提供治疗时会使用哪些恢复性材料 病人的选择。目前，有越来越多的人使用 复合树脂作为后方修复体。到目前为止，大多数研究工作 致力于提高复合树脂的耐磨性 修复术。几乎没有做出什么努力来确定可能的磨损 与复合修复体相对的尖端。这样做的具体目的是 建议的研究是评估一系列五种复合体在 在磨损上铺设不同成分和粒度的铺设系统 人牙釉质的抵抗力。该项目将分为两个阶段。 第一阶段将包括体外研究和第二阶段体内研究。 在第一阶段中，我们选择了无龋离体磨牙作为研究对象。 制备了试件，并制作了复合材料并进行了粘结。 将试件安装并插入磨损测试设备中。这件衣服 该装置可用于对所有修复体的临界评价 材料，实际上已经与过去的研究结合使用，作为 还有植入物。被选为对抗者的牙齿将由 下颌第一前磨牙的颊尖尖。小的丙烯酸树脂珠子是 用作食物的推进剂，从而产生和恢复 磨牙的表面将使用图像分析系统进行评估。 磨损面的表面积由计算机自动计算 放大倍数为x50。磨损面的表面积值 将采用单因素方差分析进行统计分析(P-1 &lt；05)。将对各自的复合树脂进行多重比较 费舍尔测试的置信度为95%。在第二期一百 复合嵌体将被插入到I类和II类窝洞预备中 在活体内。所有修复体将在90天内插入，每两个 临床医生遵循严格的临床规程。对抗者尖端和 后路修复体将在基线3个月、6个月、12个月进行评估 24个月，36个月。48个月。通过使用环氧树脂进行间接评估 树脂模型、相对尖端的磨损以及复合材料 修复将使用图像分析系统来确定。相同 L阶段使用的数据分析协议将对阶段重复 伊。