TESTING OF DENTAL RESTORATIVE MATERIAL

牙科修复材料的测试

• 批准号: 6259244
• 负责人: HENRY L YOUNG
• 金额: $ 0.27万
• 依托单位: MEHARRY MEDICAL COLLEGE
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-01 至 2003-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6259244
• 关键词: biomaterial evaluation; composite resins; dental material wear; dental materials; human subject

The long term goal of the project is to provide clinicians with scientific information which they could use to assist in making the best selection of which restorative material they would incorporate in providing treatment options for patients. Presently, there is an increase in usage of composite resins as posterior restorations. To date most research efforts have been devoted to improving the wear resistance of composite resin restorations. Little effort has been made to determine possible wear of the cusp opposing the composite restoration. The specific aim of this proposed study is to evaluate the effect of a series of five composite in lay systems, of varying composition and particle size, on the wear resistance of human enamel. This project will consist of two phases. Phase I will consist of an in vitro study and Phase II an in vivo study. In Phase I caries free extracted human molars are selected for the study. The specimen is prepared and an composite in lay fabricated and cemented. The specimen is mounted and inserted into a wear test apparatus. This wear device can be used for the critical evaluation of all restorative materials and in fact has been used in conjunction with past studies as well as implants. The teeth selected as the antagonist will consist of the buccal cusp of mandibular first premolars. Small acrylic resin beads are used to serve as the food bolus thereby generating as well as the restored surface of the molar will be evaluated using an image-analyzing system. The surface area for wear facets is calculated automatically by a computer at a magnification of x5O. The values of the surface area for wear facets will be statistically analyzed by a one-factor analysis of variance (P-1 <05). Multiple comparison among respective composite resins will be made with the Fisher test at a 95% level of confidence. In Phase II one hundred composite inlays will be inserted into Class I and II cavity preparations in vivo. All restorations will be inserted over a ninety day period by two clinicians following a strict clinical protocol. The antagonist cusp and the posterior restoration will be evaluated at baseline 3 mos., 6 mos., 12 mos., 24 mos., 36 mos. and 48 mos. By indirect evaluation using epoxy resin models, the wear of the opposing cusp as well as the composite restoration will be determined using an image analyzing system. The same protocol for analysis of data used in Phase l will be repeated for Phase Il.

该项目的长期目标是为临床医生提供科学的 他们可以使用这些信息来帮助做出最佳选择 他们在提供治疗时将采用哪些恢复材料 患者的选择。目前，使用量有所增加 复合树脂作为后牙修复体。迄今为止大多数研究工作 一直致力于提高复合树脂的耐磨性 修复。 几乎没有做出任何努力来确定可能的磨损 与复合修复体相对的尖头。此次活动的具体目的 拟议的研究是评估一系列五种复合材料的效果 具有不同成分和颗粒尺寸的铺设系统对磨损的影响 人类牙釉质的抵抗力。该项目将分为两个阶段。 第一阶段将包括体外研究，第二阶段包括体内研究。 在第一阶段，选择无龋齿的人类拔牙进行研究。 准备好样品并制造并粘合复合材料。 将样本安装并插入磨损测试装置中。这穿 设备可用于所有恢复性的关键评估 材料，事实上已与过去的研究结合使用 以及植入物。选择作为对抗牙的牙齿将包括 下颌第一前磨牙的颊尖。小丙烯酸树脂珠是 用作食物丸，从而产生和恢复 将使用图像分析系统评估臼齿的表面。 磨损面的表面积由计算机自动计算 放大倍数为50倍。磨损面的表面积值 将通过单因素方差分析（P-1 <05)。对各种复合树脂进行多重比较 Fisher 检验的置信度为 95%。第二阶段一百 复合嵌体将被插入 I 类和 II 类空腔预备中 体内。所有修复体将在九十天内由两个人插入 临床医生遵循严格的临床方案。拮抗尖峰和 后牙修复体将在基线第 3 个月、6 个月、12 个月进行评估 个月、24 个月、36 个月和 48 个月。使用环氧树脂间接评估 树脂模型、相对尖头的磨损以及复合材料 将使用图像分析系统确定修复情况。相同 第一阶段使用的数据分析协议将在第二阶段重复 伊尔。