ADULT AND SECOND GENERATION DYSLEXIA

成人和第二代阅读障碍

• 批准号: 6240998
• 负责人: DAVID L PAULS
• 金额: $ 25.68万
• 依托单位: WAKE FOREST UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 1999-01-04
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6240998
• 关键词: adult human (21+); behavior test; behavioral genetics; dyslexia; educational psychology; electrophysiology; family genetics; human subject; intelligence tests; interview; longitudinal human study; middle childhood (6-11); neuropsychological tests; neuropsychology; phenotype; psychometrics

Continued studies are proposed on a sample of 100 adults whose childhood reading history is well documented through archival information. Spouses and children of the probands will be recruited, as will some extended family members of selected, subjects. All subjects will undergo behavioral assessments, using procedures already shown to define the adult behavioral phenotype. From these assessments, the patterns of genetic transmission are examined with various analytic techniques, particularly segregation analysis. Electrophysiological studies, done in project IV on probands and their children, will be analyzed for transmission patterns of the electrophysiological phenotype.

建议对100名成年人的样本进行继续研究， 阅读历史通过档案信息被很好地记录。 配偶 先证者的子女将被招募， 选定的受试者的家庭成员。 所有受试者将进行 行为评估，使用已经显示的程序来定义成人 行为表型 通过这些评估，研究了遗传传播的模式 各种分析技术，特别是分离分析。 电生理学研究，在项目IV中对先证者及其 儿童，将分析的传播模式， 电生理表型