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EPINEPHRINE EFFECT ON SYSTEMIC INFLAMMATORY RESPONSES IN ENDOTOXEMIA

EPINEPHRINE EFFECT ON SYSTEMIC INFLAMMATORY RESPONSES IN ENDOTOXEMIA
肾上腺素对内毒素血症全身炎症反应的影响
批准号：
6245102
负责人：
STEPHEN F LOWRY
金额：
$5.36万
依托单位：
WEILL MEDICAL COLL OF CORNELL UNIV
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-02-24 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6245102
关键词：
chimeric proteins clinical research cytokine receptors endotoxins epinephrine human subject immunoglobulin G immunopharmacology inflammation intravenous administration recombinant proteins tumor necrosis factor alpha

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英文摘要
Endotoxemia is associated with the appearance of tumor necrosis factor in the circulation. To assess the role of tumor necrosis factor in the systemic inflammatory responses induced by endotoxin, healthy humans will be intravenously injected with endotoxin with or without a 30-minute intravenous infusion of a recombinant tumor necrosis factor receptor-IgG fusion protein, which is known to neutralize tumor necrosis factor activity.
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PARENTERAL GLUTAMINE DIPEPTIDE SUPPLEMENTATION
EPINEPHRINE EFFECT ON SYSTEMIC INFLAMMATORY RESPONSES IN ENDOTOXEMIA
THE EFFECT OF CORTISOL AND EPINEPHRINE ON CYTOKINE PRODUCTION IN NORMAL SUBJECTS
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