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PARENTERAL GLUTAMINE DIPEPTIDE SUPPLEMENTATION

PARENTERAL GLUTAMINE DIPEPTIDE SUPPLEMENTATION
肠外谷氨酰胺二肽补充剂
批准号：
6245101
负责人：
STEPHEN F LOWRY
金额：
$5.36万
依托单位：
WEILL MEDICAL COLL OF CORNELL UNIV
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-02-24 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6245101
关键词：
clinical research diet therapy dietary supplements dipeptides glutamine human subject human therapy evaluation muscle proteins nutrition related tag parenteral feedings striated muscles

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中文摘要
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英文摘要
Total parenteral nutrition (TPN) has been linked to conditions that promote intestinal atrophy, mucosal dysfunction and protein malnutrition. Parenterally-fed subjects also exhibit exaggerated hormone and cytokine response to endotoxin. Since addition of glutamine to parenteral formula has prevented loss of intestinal morphology in animal models and to conserve skeletal muscle protein this study will test whether supplementation of TPN with glutamine may work similarly in humans.
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