课题基金 / 基金详情

SAFETY & EFFICACY OF CLARITHROMYCIN FOR AIDS-RELATED CRYPTOSPORIDIAL DIARRHEA

SAFETY & EFFICACY OF CLARITHROMYCIN FOR AIDS-RELATED CRYPTOSPORIDIAL DIARRHEA
安全
批准号：
6245109
负责人：
ROSEMARY SOAVE
金额：
$5.36万
依托单位：
WEILL MEDICAL COLL OF CORNELL UNIV
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-02-24 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6245109
关键词：
AIDS therapy Cryptosporidium HIV infections clarithromycin clinical research cryptosporidiosis diarrhea dosage forms drug screening /evaluation gastrointestinal drug absorption human subject human therapy evaluation malabsorption parasitic disease chemotherapy pharmacokinetics xylose

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中文摘要
翻译
先前对大环内酯类药物的研究表明，这类药物可能具有
英文摘要
Previous work with macrolides suggests that this class of agents may have activity against this parasite. The aims of this study are to: (1)evaluate the safety and efficacy of ascending doses of clarithromycin (2)compare the absorption and tolerability of the tablet and liquid forms of cla rithromycin; and (3)evaluate the impact of malabsorption, as measured by d-xy-lose absorption, on the bioavailability and efficacy of clarithromycin for AID related cryptosporidial enteritis.
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会议论文
IMMUNOPATHOGENESIS OF CRYPTOSPORIDIOSIS
SAFETY & EFFICACY OF CLARITHROMYCIN FOR AIDS-RELATED CRYPTOSPORIDIAL DIARRHEA
PHASE I/II OPEN LABEL EVALUATION OF NITAZOXANIDE CRYPTOSPORIDIOSIS IN AIDS
IMMUNOPATHOGENESIS OF CRYPTOSPORIDIOSIS
国内基金
海外基金
人类和非人灵长类人隐孢子虫（Cryptosporidium hominis）的人兽共患传播机制研究
  • 批准号：
    U1404327
  • 项目类别：
    联合基金项目
  • 资助金额：
    30.0万元
  • 批准年份：
    2014
  • 负责人：
    朱惠丽
  • 依托单位：
    河南农业大学