Portable instrument for quantification and genotyping of Cryptosporidium

用于隐孢子虫定量和基因分型的便携式仪器

• 批准号: LP200200758
• 负责人: Prof Nam-Trung Nguyen
• 金额: $ 26.08万
• 依托单位: Griffith University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-10-18 至 2024-10-17
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP200200758
• 关键词: Portable; instrument; quantification; genotyping; Cryptosporidium

Cryptosporidium is a parasitic protozoan, causing more than 48,000 deaths in children under 5 and 7.2 million disability-adjusted-life-years globally. A low-cost device that rapidly detects the parasite in drinking and recreational water is needed to enable effective disease management practices. Partnering with Advanced Universal Diagnotik, Seqwater, ALS Water and Gold Coast Water, this project aims to develop a novel device, comprising advanced microfluidics and biosensing technology for parasite quantification, genotyping and viability analysis. Expected outcomes are improved Cryptosporidium management, risk prediction, and rapid mitigation of impending outbreaks. The proposed platform has a great potential for detecting other pathogens.

隐孢子虫是一种寄生原生动物，在全球范围内造成超过48，000名5岁以下儿童死亡和720万残疾调整生命年。需要一种能够快速检测饮用水和娱乐用水中寄生虫的低成本设备，以实现有效的疾病管理实践。该项目与Advanced Universal Diagnotik，Seqwater，ALS Water和黄金海岸Water合作，旨在开发一种新型设备，包括先进的微流体和生物传感技术，用于寄生虫定量，基因分型和活力分析。预期成果是改进隐孢子虫管理、风险预测和迅速缓解即将发生的疫情。所提出的平台具有检测其他病原体的巨大潜力。