GENETIC EPIDEMIOLOGY OF CANCER IN UTAH GENEALOGIES

犹他州谱系中癌症的遗传流行病学

• 批准号: 6245899
• 负责人: MARK H SKOLNICK
• 金额: $ 2.15万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-06 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6245899
• 关键词: United States; cancer risk; clinical research; family genetics; gene frequency; genetic models; human subject; molecular oncology; neoplasm /cancer epidemiology; neoplasm /cancer genetics; phenotype

The goal of this study is to identify genetic mechanisms behind familial components of cancer. Genetic and molecular mechanisms will be studied in families at risk for cancers. Study of genetic models in cancer families will help establish frequency of cancer genes in the population, penetrance of each gene for a set of cancer phenotypes and possibly identify individuals at risk.

这项研究的目的是确定家族性遗传病背后的遗传机制。 癌症的组成部分。 将研究遗传和分子机制 在有癌症风险的家庭中。 癌症遗传模型的研究 家庭将有助于建立癌症基因的频率， 群体，一组癌症表型的每个基因的突变率，以及 可能识别出处于危险中的个体。