PITUITARY-OVARIAN RESPONSES TO GNRH AGONIST TESTING IN WOMEN W/POLYCYSTIC OVARY

多囊卵巢女性对 GNRH 激动剂测试的垂体-卵巢反应

• 批准号: 6246360
• 负责人: ROBERT B JAFFE
• 金额: $ 4.89万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-02-04 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6246360
• 关键词: clinical research; diagnostic tests; endocrine disorder diagnosis; female; female reproductive system surgery; gonadotropin releasing factor; gonadotropins; hormone regulation /control mechanism; human subject; ovulation; pituitary gonadal axis; polycystic ovary syndrome; progesterone; stimulant /agonist

This study is to compare gonadotropin and 17a-hydroxyprogesterone responses to GnRH agonist testing in women with polycystic ovarian syndrome (PCOS) before and after laparoscopic ovarian cautery. This study will also determine the endocrine changes associated with the return of ovulation in women with PCOS following laparoscopic ovarian cautery. M01RR000790457 We propose to establish a regional cohort of women either with HIV infection or at high risk of acquiring it to carry out a logitudinal study of the natural history of the disease. We intend to determine: 1)spectrum and time course of the manifestations of HIV infection in women; 2)characterize changes in immunologic function among women with HIV infection; 3)investigate factors predictive of rates of progression of HIV-related illness and of survival.

本研究旨在比较促性腺激素和17 α-羟孕酮 多囊卵巢综合征患者对GnRH激动剂试验的反应 多囊卵巢综合征（PCOS）的腹腔镜卵巢烧灼术前后。 这 这项研究还将确定内分泌变化与 多囊卵巢综合征妇女腹腔镜卵巢切除术后排卵恢复 烧灼 M01RR000790457 我们建议建立一个由感染艾滋病毒的妇女 感染或有高风险获得它来执行logloggram 研究疾病的自然史。 我们打算确定： 1)艾滋病毒感染的表现谱和时间进程， 妇女; 2）描述妇女免疫功能的变化， HIV感染; 3）研究进展率的预测因素 与艾滋病相关的疾病和生存率。