CALM-PD PARALLEL GROUP DP, STUDY OF PRAMIPEXOLE AND CARBIDOPA-L IN PD

CALM-PD 平行组 DP，普拉克索和卡比多巴-L 在 PD 中的研究

• 批准号: 6113737
• 负责人: ROGER M KURLAN
• 金额: $ 1.48万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6113737
• 关键词: Parkinson's disease; antiparkinson drugs; clinical research; dopamine agonists; human subject; human therapy evaluation; mental disorder chemotherapy; nervous system disorder chemotherapy

The primary goal of this study is to compare the initial treatment with pramipexole and initial treatment with carbidopa-levbodopa in early, symptomatic PD with regard to the development of dopaminergic motor complications. Dopaminergic motor complications are defined as: "wearing-off", "on-off effects", and "dyskinesias".

本研究的主要目的是比较早期症状性PD患者初始治疗普拉克索和初始治疗卡比多巴-左旋多巴对多巴胺能运动并发症发展的影响。多巴胺能运动并发症被定义为：“逐渐消失”、“开关效应”和“运动障碍”。