NOCTURNAL TSH SURGE IN CENTRAL HYPOTHYROIDISM

中枢性甲状腺功能减退症夜间 TSH 激增

• 批准号: 6219749
• 负责人: SUSAN R ROSE
• 金额: $ 1.63万
• 依托单位: UNIVERSITY OF TENNESSEE HEALTH SCI CTR
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-16 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6219749
• 关键词: central nervous system neoplasms; child (0-11); circadian rhythms; clinical research; head /neck injury; human subject; hypothyroidism; neoplasm /cancer chemotherapy; pituitary dwarfism; secretion; thyrotropin

In this study, 60 childrens with idiopathic short stature undergo overnight study of their pattern TSH. In addition, 60 children wo have undergone treatment of CNS tumor/oncology and 60 children who have survived significant head injury will be studied. Those who are identified as having blunted TSH secretion at night will be eligible to participate in a subsequent placebo-controlled treatment phase.

在这项研究中，60 名特发性身材矮小儿童接受了过夜的 TSH 模式研究。 此外，还将对 60 名接受过中枢神经系统肿瘤/肿瘤治疗的儿童和 60 名头部严重受伤后幸存的儿童进行研究。 那些被确定在夜间 TSH 分泌减弱的人将有资格参加随后的安慰剂对照治疗阶段。