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FACTORS REGULATING NOCTURNAL TSH SURGE TEST AS PROBE FOR HYPOTHYROIDISM

FACTORS REGULATING NOCTURNAL TSH SURGE TEST AS PROBE FOR HYPOTHYROIDISM
夜间 TSH 激增测试作为甲状腺功能减退症探针的调节因素
批准号：
6265377
负责人：
SUSAN R ROSE
金额：
$2.24万
依托单位：
UNIVERSITY OF NEW MEXICO
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6265377
关键词：
biomarker central nervous system child (0-11) child physical development chronic disease /disorder circadian rhythms clinical research endocrine disorder diagnosis hormone biosynthesis human subject hypothalamic pituitary axis hypothyroidism longitudinal human study nerve injury pituitary dwarfism thyrotropin

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中文摘要
翻译
慢性疾病、中枢神经系统损伤、生长激素缺乏和特发性矮小可能存在下丘脑-垂体-甲状腺轴的异常。这可能在夜间的低促甲状腺激素激增中很明显。TSH激增将在患有这些疾病的儿童中进行测试。低TSH峰和匹配的TSH峰正常的患者将接受6个月的左旋甲状腺素治疗，并比较他们的生长和临床反应。
英文摘要
An abnormality of the hypothalamic-pituitary-thyroid axis may be present in chronic illness, CNS injury, growth hormone deficiency, and idiopathic short stature. This may be evident in a low nocturnal TSH surge. The TSH surge will be tested in children with these conditions. Patients with a low TSH surge and matched patients with a normal surge will be treated with levothyroxine for 6 months and their growth and clinical responses compared.
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NOCTURNAL TSH SURGE IN CENTRAL HYPOTHYROIDISM
NOCTURNAL TSH SURGE IN CENTRAL HYPOTHYROIDISM
CLINICAL TRIAL OF LHRHA IN PUBERTAL PATIENTS WITH SHORT STATURE
  • 批准号：
    6118730
  • 项目类别：
  • 资助金额：
    $2.24万
  • 财政年份：
    1998
  • 负责人：
    SUSAN R ROSE
  • 依托单位：
    UNIVERSITY OF NEW MEXICO
CLINICAL TRIAL OF LHRHA IN PUBERTAL PATIENTS WITH SHORT STATURE
  • 批准号：
    6249889
  • 项目类别：
  • 资助金额：
    $1.65万
  • 财政年份：
    1997
  • 负责人：
    SUSAN R ROSE
  • 依托单位：
    UNIVERSITY OF NEW MEXICO
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