ACTIGRAPHY AND POLYSOMNOGRAPHY IN ASTHMA

哮喘的体动描记法和多导睡眠图

• 批准号: 6115809
• 负责人: David M Rapoport
• 金额: $ 2.1万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6115809
• 关键词: asthma; clinical research; comorbidity; diagnosis design /evaluation; human subject; immunopathology diagnosis; patient monitoring device; polysomnography; respiratory disorder diagnosis; sleep disorders

This study seeks to test the hypothesis that actigraphy can detect changes in nocturnal asthma that correlate with symptoms. We will confirm that optimal medical therapy improves sleep quality in patients with nocturnal asthma. We will then attempt to demonstrate that actigraphy will detect the fragmented sleep documented by polysomnography in asthmatics with nocturnal symptoms and the improved sleep achieved by optimizing medical management. Patients with nocturnal asthma will wear the actigraph for three nights, one of which will include traditional polysomnography. Their medications will be optimized, and in two weeks the process will be repeated. Pulmonary function tests will be done at entry and at two weeks time. Data will be analyzed by a unique analytic measure called Frequency Analysis of Consecutive Epochs (FACE) that we have designed. We will compare these results with those from polysomnography, an asthma questionnaire and a sleep questionnaire.

这项研究旨在验证这一假设，即腕动记录仪可以检测与症状相关的夜间哮喘变化。 我们将证实最佳的药物治疗可以改善夜间哮喘患者的睡眠质量。 然后，我们将试图证明，体动记录仪将检测多导睡眠图记录的有夜间症状的哮喘患者的碎片睡眠，并通过优化医疗管理来改善睡眠。 夜间哮喘患者将佩戴活动记录仪三个晚上，其中一个晚上将包括传统的多导睡眠图。 他们的药物将得到优化，并在两周内重复这一过程。 将在入组时和两周后进行肺功能检查。 数据将通过我们设计的称为连续时期频率分析（FACE）的独特分析方法进行分析。 我们将把这些结果与多导睡眠图、哮喘问卷和睡眠问卷的结果进行比较。