TOTAL ENERGY EXPENDITURE IN CYSTIC FIBROSIS

囊性纤维化的总能量消耗

• 批准号: 6117814
• 负责人: CATHERINE LEITCH
• 金额: $ 1.7万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6117814
• 关键词: bioenergetics; child (0-11); clinical research; cystic fibrosis; developmental nutrition; human subject; nutrient requirement; nutrition related tag

We will measure resting energy expenditure and total energy expenditure in 10-12 month old infants and 7- 8 year old children with cystic fibrosis. These two groups have very different physical activity patterns. Infants are not yet ambulatory, so if their resting energy expenditures are higher than those of healthy infants, they are unable to compensate by lowering their physical activity. Therefore, their actual total energy needs may be much higher that those of healthy infants. In contrast, children may compensate for higher resting energy expenditure by decreased physical activity. However, the extent of this compensation is unknown. Knowledge of the total energy expenditures of these patients is necessary to accurately gauge their energy requirements. Our long-term objective is to gain insight into the total energy needs of CF patients in order to provide appropriate nutritional support. The information obtained in this project will provide us with a valuable foundation from which to design future dietary therapies. While early and appropriate dietary intervention is important in CF patients of any age, it is crucial in infants and children who are still growing and developing.

我们将在年测量静息能量消耗和总能量消耗 10-12月龄婴儿和7-8岁儿童囊性纤维化。 这两组人的体力活动模式截然不同。婴儿 还不能活动，所以如果他们的静息能量消耗更高 与健康婴儿相比，他们不能通过降低 他们的体力活动。因此，他们的实际总能源需求可能是 远远高于健康婴儿的水平。相比之下，儿童可能会 通过减少体力活动来补偿更高的静息能量消耗 活动。然而，这一补偿的程度尚不清楚。 了解这些患者的总能量消耗是必要的。 以准确估计他们的能源需求。我们的长期目标是 了解慢性萎缩性胃炎患者的总能量需求 提供适当的营养支持。在本文件中获得的信息 该项目将为我们提供一个宝贵的设计基础 未来的饮食疗法。虽然及早进行适当的饮食干预 对任何年龄段的CF患者都很重要，对婴儿和 仍在成长和发展中的儿童。