TOTAL ENERGY EXPENDITURE IN CYSTIC FIBROSIS

我们将测量静息能量消耗和总能量消耗， 患有囊性纤维化的10-12个月大的婴儿和7- 8岁的儿童。 这两个群体有非常不同的身体活动模式。婴儿 还不能走动，所以如果他们的静息能量消耗更高， 与健康婴儿相比，他们无法通过降低 他们的身体活动。因此，它们的实际总能量需求可能是 远远高于健康婴儿。相反，儿童可能 通过减少体力消耗来补偿较高的静息能量消耗 活动然而，这种补偿的程度是未知的。 了解这些患者的总能量消耗是必要的 来精确测量它们的能量需求我们长远的目标是 了解CF患者的总能量需求， 提供适当的营养支持。本报告中获得的信息 项目将为我们提供一个宝贵的基础，从设计 未来的饮食疗法虽然早期和适当的饮食干预 在任何年龄的CF患者中都很重要，在婴儿中至关重要， 孩子们还在成长和发展。

We will measure resting energy expenditure and total energy expenditure in 10-12 month old infants and 7- 8 year old children with cystic fibrosis. These two groups have very different physical activity patterns. Infants are not yet ambulatory, so if their resting energy expenditures are higher than those of healthy infants, they are unable to compensate by lowering their physical activity. Therefore, their actual total energy needs may be much higher that those of healthy infants. In contrast, children may compensate for higher resting energy expenditure by decreased physical activity. However, the extent of this compensation is unknown. Knowledge of the total energy expenditures of these patients is necessary to accurately gauge their energy requirements. Our long-term objective is to gain insight into the total energy needs of CF patients in order to provide appropriate nutritional support. The information obtained in this project will provide us with a valuable foundation from which to design future dietary therapies. While early and appropriate dietary intervention is important in CF patients of any age, it is crucial in infants and children who are still growing and developing.