COCAINE EFFECTS IN HUMANS--PHYSIOLOGY AND BEHAVIOR

可卡因对人类的影响——生理和行为

• 批准号: 6219987
• 负责人: MARIAN W FISCHMAN
• 金额: $ 0.04万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6219987
• 关键词: alcoholism /alcohol abuse; clinical research; cocaine; drug abuse chemotherapy; drug addiction; drug interactions; human subject; human therapy evaluation; opiate alkaloid; self medication; substance abuse related behavior

Cocaine abuse is now polydrug abuse, with cocaine-opiate use becoming a major problem. The focus will be on evaluating cocaine self-administration in opiate dependent people, both before and after they have received their daily maintenance dose, with the goal of evaluating potential new treatment medications as they appear. A second focus of this research will be on cocaine self-administration in combination with ethanol in people who report heavy ethanol use.

可卡因滥用现在是多种药物滥用，可卡因-阿片类药物的使用成为一个主要问题。重点将是评估阿片类药物依赖者在接受每日维持剂量之前和之后的可卡因自我给药情况，目的是评估可能出现的新治疗药物。这项研究的第二个重点将是报告大量使用乙醇的人的可卡因自我给药与乙醇结合。