MUCOSAL STRATEGIES FOR GENERAL IMMUNITY AGAINST SEXUALLY TRANSMITTED DISEASE

针对性传播疾病的一般免疫的粘膜策略

• 批准号: 6116836
• 负责人: WILLIAM H KUTTEH
• 金额: --
• 依托单位: UNIVERSITY OF TENNESSEE HEALTH SCI CTR
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-12-01 至 1999-08-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6116836
• 关键词: behavioral /social science research tag; blood chemistry; cervical /vaginal smear; clinical research; disease /disorder prevention /control; drug screening /evaluation; female reproductive system; hormone regulation /control mechanism; human subject; immunization; immunosuppressive; microorganism disease chemotherapy; mucosal immunity; patient care planning; saliva; sexually transmitted diseases; women's health

This study proposes to (1) evaluate the effect of the endogenous and exogenous hormonal status on the immune system of the genital tract (2) evaluate the effect of local estrogens, spermicides, and anti-fungal agents on genital tract immunity and (3) evaluate the relative contributions of uterine cervical and vaginal B and T cells and their products to the immune system of the genital tract before and after specific mucosal immunization.

本研究提出(1)评估内源性和