DEVELOPMENT OF TENSILE NECK INJURY CRITERIA FOR PEDIATRIC POPULACE

制定儿科颈部拉伸损伤标准

• 批准号: 6277627
• 负责人: RANDAL P CHING
• 金额: $ 7.23万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-01 至 1999-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6277627
• 关键词: Primates; animal tissue; bioengineering /biomedical engineering; disease /disorder prevention /control; growth /development; injury; model design /development; skeletal system

Pediatric spinal cord injury is a devastating trauma outcome with life-long debilitating consequences. Each year in the United States alone, over 1000 children under the age of 15 incur spinal cord injuries; approximately 10% are fatal, while 41% of these children sustain varying degrees of irreversible neurological deficit. These injuries most often occur in the cervical region (80%) and, compared with all other pediatric injuries, result in the largest AIS scores, highest mortality, and longest hospital stays. Many of these injuries are a result of tensile forces applied to the spine from the deployment of air bags. Few biomechanics studies have addressed these air-bag-related injuries; therefore our current project is aimed at determining neck injury criteria for the pediatric spine. This program will determine the tensile strength of cadaver baboon cervical spines. We are testing the hypothesis that younger age specimens have less strength but more ductility characteristics than adult specimens. Also, we will examine the failure patterns and mechanisms of injury that might occur at different ages. Therefore, the ultimate goal is to obtain age scaling laws for cervical spine tensile failure characteristics so that they may be applied in injury prevention strategies for the human pediatric population. This project, which has just gotten under way, is already generating excellent results. Using cervical spine tissue from baboon cadavers, we are beginning to obtain data for the validation of test dummies and computer models, the development of injury prevention schemes, and the evolution of better injury management and care strategies.

小儿脊髓损伤是一种毁灭性的创伤结果， 终身衰弱的后果。 美国每年 仅1000多名15岁以下的儿童因脊髓损伤 受伤;大约10%是致命的，而这些儿童中有41% 承受着不同程度的不可逆的神经损伤。 这些 损伤最常发生在颈部（80%）， 所有其他儿科损伤，导致最大的AIS评分， 死亡率最高住院时间最长 这些伤口中有许多 是由于施加在脊柱上的张力， 使用安全气囊。 很少有生物力学研究解决了这些问题 安全气囊相关的伤害;因此，我们目前的项目旨在 确定儿童脊柱颈部损伤标准。 这 程序将确定狒狒尸体颈部的拉伸强度 刺 我们正在验证一个假设，即年轻的样本 强度较低但延展性较好。 此外，我们将研究故障模式和损伤机制 可能发生在不同的年龄。 因此，最终目标是 获得颈椎拉伸破坏的年龄比例律 特点，使他们可以应用于伤害预防 人类儿科人群的策略。 该项目 刚刚开始，已经产生了很好的结果。 利用狒狒尸体的颈椎组织，我们开始 获得用于验证测试假人和计算机模型的数据， 伤害预防计划的发展，以及 更好的伤害管理和护理策略。