DEVELOPMENT OF RENAL FUNCTION TEST--PARA AMINOHIPPURATE EXCRETION TEST

肾功能试验的进展--对氨基马尿酸排泄试验

• 批准号: 6278762
• 负责人: Robert A Star
• 金额: $ 2.47万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6278762
• 关键词: clinical research; diagnostic tests; excretion; human subject; kidney function; method development; p aminohippurate

Current tests of renal function estimate or measure glomerular function. Unfortunately, there are no accepted tests of tubular function. Therefore a more general test that assesses both glomerular and tubular function would be helpful in the following settings: (1) to accurately determine the extent of renal damage during acute renal failure as a guide to beginning specific therapy, and (2) to determine if an agent alters the rate of recovery of renal function. The purpose of these pilot studies is to develop the test, determine its validity, reproducibility, and behavior in several models of renal injury.

目前的肾功能测试估计或测量肾小球功能。