VLDL APO-B-100 SYNTHESIS IN NON-ALCOHOLIC STEATOHEPATITIS

非酒精性脂肪性肝炎中 VLDL APO-B-100 的合成

• 批准号: 6278631
• 负责人: M CHARLTON
• 金额: $ 2.03万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6278631
• 关键词: apolipoprotein B; blood lipoprotein biosynthesis; clinical research; hepatitis; human subject; liver metabolism; very low density lipoprotein

This protocol is designed to determine the pathophysiology of nonalcoholic steatohepatitis (NASH) and specifically to determine whether the hepatic synthesis of VLDL 1po B-100 is attentuated in patients with NASH, causing defective removal of synthesized triglycerides from hepatocytes.

本方案旨在确定 非酒精性脂肪性肝炎（NASH），特别是确定 VLDL 1 po B-100的肝合成是否减弱， NASH患者，导致合成的 肝细胞中的甘油三酯。