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SYNCHROTRON CRYSTALLOGRAPHY OF RNA 3 TERMINAL PHOSPHATE CYCLASE

SYNCHROTRON CRYSTALLOGRAPHY OF RNA 3 TERMINAL PHOSPHATE CYCLASE
RNA 3 末端磷酸环化酶的同步加速器晶体学
批准号：
6120417
负责人：
ALEX WLODAWER
金额：
$0.0万
依托单位：
ALBERT EINSTEIN COLLEGE OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-09-30 至 1999-08-31
来源：
https://reporter.nih.gov/project-details/6120417
关键词：
biological products biomedical resource enzymes spectrometry

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中文摘要
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英文摘要
RNA 3'-terminal phosphate cyclase catalyzes the ATP-dependent conversion of the 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. It is an essential enzyme and conserved across all kingdoms. Data were collected for a crystal of RNA 3' Phosphate cyclase soaked in the solution containing 10mM AMP. Data collection statistics: 97% completeness at 3 A resolution and the R-factor (20 A - 3A) is 5.7. Unfortunately, it does not appear that AMP was bound with detectable occupancy.
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  • 批准号：
    6307523
  • 项目类别：
  • 资助金额：
    $0.82万
  • 财政年份：
    1999
  • 负责人：
    ALEX WLODAWER
  • 依托单位：
    ROCKEFELLER UNIVERSITY
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