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MEASUREMENTS OF MULTIPHOTON CROSS SECTIONS FOR SEVERAL PHOTOSENSITIZERS

MEASUREMENTS OF MULTIPHOTON CROSS SECTIONS FOR SEVERAL PHOTOSENSITIZERS
几种光敏剂的多光子截面测量
批准号：
6121887
负责人：
MICHAEL G NICHOLS
金额：
$1.36万
依托单位：
CORNELL UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-09-30 至 1999-08-31
来源：
https://reporter.nih.gov/project-details/6121887
关键词：
bioengineering /biomedical engineering biological products biomedical resource lasers technology /technique

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英文摘要
During the previous year we have completed the measurement of the two-photon action cross section for Photofrin and have begun additional measurements for other photosensitizing compounds. Under typical imaging conditions, Photofrin is observed to change from one-photon to two-photon excitation as the excitation wavelength is varied from 700-750 nm. This has been verified by measuring the edge response from a solution of Photofrin dissolved in methanol as a function of wavelength. For wavelengths between 750 and 980 nm the two-photon action cross section decreases from approximately 0.6 GM to 0.2 GM. Both absolute and relative cross section measurements have been made and found to agree. The two-photon excitation cross section of other photosensitizers are at various stages of completion and described and accounted for elsewhere.
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