Does exercise increase skeletal muscle insulin sensitivity via nitric oxide?

运动是否会通过一氧化氮增加骨骼肌胰岛素敏感性？

• 批准号: nhmrc : 1012181
• 负责人: Prof Glenn Mcconell
• 金额: $ 37.53万
• 依托单位: Victoria University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/does-exercise-increase-nitric-oxide/109640
• 关键词: Does; exercise; increase; skeletal; muscle

Almost one in four Australian adults have either diabetes or impaired glucose metabolism. A major benefit of exercise is that it increases the sensitivity of muscle to insulin for many hours after the exercise is completed. We don't fully understand the mechanisms that exercise increases muscle insulin sensitivity. If we discover how nitric oxide production during exercise is involved, drugs that mimic these exercise effects may be designed to benefit those with diabetes.

几乎四分之一的澳大利亚成年人患有糖尿病或糖代谢障碍。运动的一个主要好处是，在运动结束后的几个小时内，它会增加肌肉对胰岛素的敏感性。我们并不完全了解运动增加肌肉胰岛素敏感性的机制。如果我们发现运动过程中一氧化氮的产生是如何参与的，模仿这些运动效果的药物可能会被设计出来，使糖尿病患者受益。