CORE--LABORATORY ANIMALS
CORE--LABORATORY ANIMALS
批准号:
6311457
负责人:
JAMES O STEVENS
金额:
$14.76万
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-05-01 至 2001-06-30
中文摘要
衰老和阿尔茨海默氏症研究中心实验动物中心运作
英文摘要
The Aging and Alzheimer's Research Center Laboratory Animal Core operates
as a shared resource which facilitates, enriches and coordinates animal
model studies for four of the five component projects in the Center
proposal. This Core has, over previous grant and project periods,
developed and maintained barrier-sustained, disease-free colonies of
conventional, aged, ultra-aged and lifetime (more 39 months) caloric
restricted, neurologically modeled rats in order to reduce data
compromising animal variables for new and ongoing studies. We have
eliminated infectious agents from all experimental colonies, constructed
and renovated new barriered housing areas, established improved
environmental conditions for housing behavioral modeled research animals
with behavioral testing laboratories contiguous to animal housing rooms.
One specific aim of this core component is to continue to provide
specialized maintenance of barrier sustained transplant, conventional,
caloric-restricted, 6-OHDA modeled and control aged rats. The core will
continue to facilitate all aspects of animal model studies as previously
developed and implemented. A second specific aim is to provide other core
services to Aging Center investigators including comprehensive gross and
histopathological evaluations of experimental animals, serological
surveillance to document a continuing virus (especially parvovirus) and
mycoplasma disease-free status and continuous consultation on laboratory
animal genetics, modeling and spontaneous disease evaluations in aged rats.
A third specific aim is to maintain and provide Center investigators with
nutritionally (caloric) restricted, aged (more 30 months) Fisher 344 rats.
In the fourth specific aim, the Core Director will develop a nw, automated
data base which will include, monitor and track all experimental animals
used in all projects. All project animals will be uniquely identified with
implanted with electronic, transponder microchips. This database will be
networked to and be accessible by all Center investigators. The Core will
coordinate the use of all animals within and between projects in order to
maximize the efficiency of animal use and eliminate any potential
unnecessary and redundant animal use.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
STRUCTURAL ANALYSIS OF INFLUENZA VIRAL PROTEINS
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批准号:8362412
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项目类别:
-
资助金额:$0.06万
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财政年份:2011
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负责人:JAMES O STEVENS
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依托单位:
LABORATORY ANIMAL CORE
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批准号:7229265
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项目类别:
-
资助金额:$7.63万
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财政年份:2006
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负责人:JAMES O STEVENS
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依托单位:
CORE--LABORATORY ANIMALS
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批准号:6664426
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项目类别:
-
资助金额:$25.04万
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财政年份:2002
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负责人:JAMES O STEVENS
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依托单位:
CORE--LABORATORY ANIMALS
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批准号:6589971
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项目类别:
-
资助金额:$25.04万
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财政年份:2002
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负责人:JAMES O STEVENS
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依托单位:
CORE--LABORATORY ANIMALS
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批准号:6503423
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项目类别:
-
资助金额:$25.04万
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财政年份:2001
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负责人:JAMES O STEVENS
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依托单位:
CORE--IMMUNODEFICIENT RODENT /LABORATORY ANIMAL FACILITY
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批准号:6459550
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项目类别:
-
资助金额:$6.18万
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财政年份:2001
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负责人:JAMES O STEVENS
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依托单位:
CORE--IMMUNODEFICIENT RODENT /LABORATORY ANIMAL FACILITY
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批准号:6506237
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项目类别:
-
资助金额:$6.18万
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财政年份:2000
-
负责人:JAMES O STEVENS
-
依托单位:
CORE--IMMUNODEFICIENT RODENT /LABORATORY ANIMAL FACILITY
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批准号:6504956
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项目类别:
-
资助金额:$6.18万
-
财政年份:2000
-
负责人:JAMES O STEVENS
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依托单位:
CORE--LABORATORY ANIMALS/TRANSGENICS
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批准号:6300307
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项目类别:
-
资助金额:$21.52万
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财政年份:2000
-
负责人:JAMES O STEVENS
-
依托单位:
CORE--IMMUNODEFICIENT RODENT /LABORATORY ANIMAL FACILITY
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批准号:6657506
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项目类别:
-
资助金额:$6.18万
-
财政年份:2000
-
负责人:JAMES O STEVENS
-
依托单位:
CORE--IMMUNODEFICIENT RODENT /LABORATORY ANIMAL FACILITY
-
批准号:6367963
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项目类别:
-
资助金额:$15.67万
-
财政年份:2000
-
负责人:JAMES O STEVENS
-
依托单位:
CORE--LABORATORY ANIMALS/TRANSGENICS
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批准号:6102443
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项目类别:
-
资助金额:$21.52万
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财政年份:1999
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负责人:JAMES O STEVENS
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依托单位:
CORE--LABORATORY ANIMALS/TRANSGENICS
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批准号:6217372
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项目类别:
-
资助金额:$21.52万
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财政年份:1999
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负责人:JAMES O STEVENS
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依托单位:
CORE--LABORATORY ANIMALS
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批准号:6097983
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项目类别:
-
资助金额:$14.76万
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财政年份:1999
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负责人:JAMES O STEVENS
-
依托单位:
CORE--IMMUNODEFICIENT RODENT /LABORATORY ANIMAL FACILITY
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批准号:6102830
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项目类别:
-
资助金额:$15.67万
-
财政年份:1999
-
负责人:JAMES O STEVENS
-
依托单位:
CORE--IMMUNODEFICIENT RODENT /LABORATORY ANIMAL FACILITY
-
批准号:6217433
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项目类别:
-
资助金额:$15.67万
-
财政年份:1999
-
负责人:JAMES O STEVENS
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依托单位:
CORE--IMMUNODEFICIENT RODENT /LABORATORY ANIMAL FACILITY
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批准号:6366916
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项目类别:
-
资助金额:$15.67万
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财政年份:1999
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负责人:JAMES O STEVENS
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依托单位:
CORE--LABORATORY ANIMALS
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批准号:6112036
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项目类别:
-
资助金额:$12.74万
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财政年份:1998
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负责人:JAMES O STEVENS
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依托单位:
CORE--IMMUNODEFICIENT RODENT /LABORATORY ANIMAL FACILITY
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批准号:6269585
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项目类别:
-
资助金额:$16.24万
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财政年份:1998
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负责人:JAMES O STEVENS
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依托单位:
CORE--LABORATORY ANIMALS
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批准号:6267224
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项目类别:
-
资助金额:$14.19万
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财政年份:1998
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负责人:JAMES O STEVENS
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依托单位:
海外基金