EVOKED POTENTIAL G-WAVE DETECTION FOR SLEEP ANALYSIS

这项研究的目标是开发一种创新的新方法，利用听觉诱发反应来衡量唤醒状态、睡眠深度和睡眠障碍的重要因素。新方法利用高于平常的刺激率来记录人类头皮的 G 波；将与 EEG、EOG 和 EMG 电极记录的睡眠深度的标准测量值进行比较。由于我们的第一阶段研究表明 G 波受到睡眠的影响，并且由于 G 波提供了大脑活动的新测量方法，因此这里提出的研究将确定这些新测量方法的变化与睡眠标准测量方法的变化的相关性。其他研究将寻找最佳刺激和刺激参数。 G 波可能为诊断和治疗睡眠障碍患者的临床医生提供一种新工具。

The goal of this research is to develop an innovative new method of using auditory evoked responses as a measure of state of arousal, of depth of sleep, and of factors of importance in sleep disorders. The new method, utilizing higher-than-usual stimulation rates to record G-waves from the scalps of humans; will be compared with standard measures of depth of sleep recorded from EEG, EOG, and EMG electrodes. Since our Phase I studies suggest that G-waves are affected by sleep, and since G-waves provide new measures of brain activity, the research proposed here will determine the correlations of changes in these new measures with changes in standard measures of sleep. Other studies will look for optimum stimulus and stimulation parameters. G-waves may provide a new tool for clinicians who are diagnosing and treating patients with sleep disorders.