EFFECT OF EXERCISE TRAINING ON DIASTOLIC FUNCTION

运动训练对舒张功能的影响

• 批准号: 6122724
• 负责人: DALANE W KITZMAN
• 金额: $ 3.88万
• 依托单位: WAKE FOREST UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6122724
• 关键词: cardiovascular disorder prevention; cardiovascular function; clinical research; congestive heart failure; exercise; heart contraction; human old age (65+); human subject; human therapy evaluation; intracardiac volume

Diastolic dysfunction is a common cause of congestive heart failure (CHF), particularly among the elderly. Exercise intolerance is a prominent sympton of CHF and an important cause of disability. The aim of this study is to test the hypotheses that exercise intolerance is associated with diminished ability to increase end-diastolic volume during exercise, and that exercise training will improve exercise tolerance and end- diastolic volume (LV distensibility).

舒张功能障碍是充血性心力衰竭（CHF）的常见原因， 尤其是老年人。 运动不耐症是一个突出的 CHF症状和残疾的重要原因。 的目的 这项研究旨在验证运动不耐症与 随着在运动期间增加舒张末期容积的能力降低， 运动训练可以提高运动耐力， 舒张期容积（LV扩张性）。