HYPOPITUITARY CONTROL AND COMPLICATIONS

垂体功能低下的控制和并发症

• 批准号: 6305907
• 负责人: DAVID L KLEINBERG
• 金额: $ 2.1万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2000-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6305907
• 关键词: clinical research; endocrine disorder chemotherapy; hormone therapy; human subject; human therapy evaluation; longitudinal human study; pituitary dwarfism; skeletal disorder chemotherapy; somatotropin

The primary objective of this study is to document the long-term safety outcomes in somatotropin-deficient adults who are given somatropin replacement therapy as compared to similar patients who elect not to be treated with somatropin replecement therapy. The secondary goals of the study are to establish specific algorithms for safe and effective somatropin dosage in adults and to evaluate the effect of somatropin replacement therapy in conjunction with other hormonal therapies.

本研究的主要目的是记录与选择不接受生长激素替代治疗的类似患者相比，接受生长激素替代治疗的生长激素缺乏成人的长期安全性结局。 本研究的次要目的是建立成人中安全有效的重组人生长激素剂量的特定算法，并评价重组人生长激素替代治疗与其他激素治疗联合使用的效果。