NEW APPROACHES TO THE EARLY DIAGNOSIS/DETECTION OF RECURRENCE OF ACROMEGALY

肢端肥大症复发的早期诊断/检测新方法

• 批准号: 6115686
• 负责人: DAVID L KLEINBERG
• 金额: $ 2.1万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6115686
• 关键词: acromegaly; bioassay; clinical research; clinical trials; diagnosis design /evaluation; early diagnosis; glucose tolerance test; human subject; pituitary disorder diagnosis; radioimmunoassay; relapse /recurrence; somatotropin

The objective of this protocol is to assess the 24-h secretory pattern of growth hormone (GH) and GH response to glucose challenge in normal as well as untreated acromegalic patients, comparing standard radioimmunoassay measurements of GH with those made with a highly sensitive radioimmunetric assay and bioassay technique.

该协议的目的是评估正常和未经治疗的肢端肥大症患者生长激素 (GH) 的 24 小时分泌模式和 GH 对葡萄糖挑战的反应，将 GH 的标准放射免疫测定测量与使用高灵敏度放射免疫测定和生物测定技术进行的测量进行比较。