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LANREOTIDE (IPSTYL) IN " DENOVO" ACROMEGALICS

LANREOTIDE (IPSTYL) IN " DENOVO" ACROMEGALICS
“DENOVO”ACROMEGALICS 中的兰瑞肽 (IPSTYL)
批准号：
6264598
负责人：
DAVID L KLEINBERG
金额：
$2.1万
依托单位：
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6264598
关键词：
acromegaly clinical research drug screening /evaluation endocrine disorder chemotherapy hormone therapy human subject human therapy evaluation insulinlike growth factor neoplasm /cancer chemotherapy peptide hormone analog somatostatin somatotropin

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中文摘要
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英文摘要
The objectives of this open label, non-randomized protocol are to investigate the safety and efficacy of lanreotide (IPSTYL), a synthetic analogue of somatostatin, in the treatment of acromegaly. Subjects will receive drug up to four months. Normalization of GH and IGF-1 levels will be used to determine efficacy. Secondary objectives will be to investigate the safety and efficacy of lancreotide with respect to tumor size, symptoms, adverse events, and reduction of GH levels to < 5ng/ml if normalization is not possible.
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会议论文
SURGICAL DEBULKING PLUS OCTREOTIDE VERSUS OCTREOTIDE ALONE IN ACROMEGALY
PREVALENCE OF GROWTH HORMONE DEFICIENCY & RANGES OF IGF-1 IN NORMAL ELDERLY
PREVALENCE OF GROWTH HORMONE DEFICIENCY & RANGES OF IGF-1 IN NORMAL ELDERLY
Prevalence of Growth Hormone Deficiency & Ranges of IGF-1 in Normal Elderly
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