System for Localization Tumor Margins During Surgery

描述(由申请人提供)：最新技术发展和 公众对常规乳房X光检查必要性的认识不断提高 导致检测到的细小的，通常是不可触摸的 乳房病变。不幸的是，手术工具的发展速度已经 没有跟上诊断工具的发展和这些工具的移除 小病变仍然是一个困难、耗时的过程，容易发生 失败了。 这项提案涉及一种持续发展的系统，使外科医生能够 乳房保乳手术中准确识别肿瘤边缘位置 手术和针头定位乳房活组织检查程序。在第一阶段， 构建了系统的原型版本，并在 模拟乳房病变。该测试表明，该系统具有 有可能提高这些程序的准确性，并减少 由于切除不全或遗漏病变而失败的手术。同相 将开发手持版本的系统，并在各种不同的平台上进行测试 代表临床实践中所遇到的那些肿瘤几何形状。 建议的商业应用： 这项技术的商业潜力很大。克里尔已经制作了一个商业广告 旨在将该技术推向市场的合作伙伴关系。

DESCRIPTION (Provided by Applicant): Recent technological developments and increased public awareness of the need for routine mammographic screening have resulted in a dramatic increase in the detection of small, often nonpalpable breast lesions. Unfortunately, the pace of development of surgical tools has not kept pace with development of the diagnostic tools and removal of these small lesions remains a difficult, time consuming process that is prone to failure. This proposal addresses continued development of a system to allow surgeons to accurately identify the position of tumor margins during breast conservation surgery and needle-localization breast biopsy procedures. In Phase I, a prototype version of the system was constructed and successfully tested on simulated breast lesions. This testing demonstrated that the system has the potential to increase the accuracy of these procedures and reduce the number of surgeries that fail due to incomplete resections or missed lesions. In Phase II, a handheld version of the system will be developed and tested on a variety of tumor geometries representative of those encountered in clinical practice. PROPOSED COMMERCIAL APPLICATION: The commercial potential of this technology is significant. Creare has formed a commercial partnership intended to bring this technology to market.