Gastrointestinal Transit Measurement System

胃肠道传输测量系统

• 批准号: 7116207
• 负责人: DAVID B KYNOR
• 金额: $ 36.6万
• 依托单位: CREARE, LLC
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-02-01 至 2009-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7116207
• 关键词: bioimaging /biomedical imaging; biomedical equipment development; clinical biomedical equipment; clinical research; gastrointestinal absorption /transport; gastrointestinal imaging /visualization; gastrointestinal motility /pressure; human subject; image processing; three dimensional imaging /topography

DESCRIPTION (provided by applicant): Gastrointestinal motility disorders are a significant health problem accounting for millions of physician visits each year. In many patients, measurement of gastrointestinal transit can provide important diagnostic information. However, current transit measurement techniques involve radiation and cannot make the long-duration, highly-detailed recordings needed to fully evaluate patients. The goal of this project is development of a new technique for measurement of gastrointestinal transit in patients with motility disorders. The technique captures the fine details of gastrointestinal transit, does not involve radiation, and is capable of making recordings for extended periods while patients undergo their daily routines. In Phase I of this project, a prototype of the Gastrointestinal Transit Measurement System (GTMS) was constructed and successfully tested in the laboratory. In Phase II, the system will be enhanced to support operation on fully ambulatory subjects and evaluated using volunteer subjects with normal gastrointestinal function.

描述（由申请人提供）：胃肠道动力障碍是一个严重的健康问题，每年有数百万医生就诊。在许多患者中，测量胃肠道传输可以提供重要的诊断信息。然而，目前的过境测量技术涉及辐射，无法进行充分评估患者所需的长时间，高度详细的记录。 本项目的目标是开发一种新的技术，用于测量胃肠动力障碍患者的胃肠传输。该技术捕捉胃肠道传输的细节，不涉及辐射，并且能够在患者进行日常活动时长时间记录。 在该项目的第一阶段，构建了胃肠传输测量系统（GTMS）的原型，并在实验室中成功进行了测试。在第II阶段，该系统将得到增强，以支持对完全非卧床受试者的操作，并使用胃肠道功能正常的志愿受试者进行评价。