Gastrointestinal Transit Measurement System

胃肠道传输测量系统

• 批准号: 6583701
• 负责人: DAVID B KYNOR
• 金额: $ 9.94万
• 依托单位: CREARE, LLC
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-02-01 至 2004-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6583701
• 关键词: bioimaging /biomedical imaging; biomedical equipment development; diagnosis design /evaluation; gastrointestinal absorption /transport; gastrointestinal disorder diagnosis; gastrointestinal imaging /visualization; gastrointestinal motility /pressure; image processing; three dimensional imaging /topography

DESCRIPTION (provided by applicant): Gastrointestinal motility disorders are a significant health problem accounting for millions of physician visits each year. In many patients, measurement of gastrointestinal transit can provide important diagnostic information. However, current transit measurement techniques involve radiation and cannot make the long-duration, highly detailed recordings needed to fully evaluate patients. The goal of this project is the development of a new technique for outpatient measurement of gastrointestinal transit in patients with motility disorders. The technique captures the fine details of gastrointestinal transit, does not involve radiation, and is capable of making recordings for extended periods while patients undergo their daily routines. In Phase I of this project, a prototype of the Gastrointestinal Transit Measurement System (GTMS) will be constructed and tested in the laboratory. Testing will concentrate on determining the accuracy of the capsule tracking system and the ability of the system to capture transient movements. In Phase II, clinical demonstration testing will be conducted on volunteer subjects with normal and abnormal gastrointestinal function.

描述（由申请人提供）：胃肠动力障碍是一个重大的健康问题，每年导致数以百万计的医生就诊。对于许多患者来说，胃肠道传输的测量可以提供重要的诊断信息。 然而，当前的传输测量技术涉及辐射，无法进行全面评估患者所需的长时间、高度详细的记录。该项目的目标是开发一种新技术，用于门诊测量运动障碍患者的胃肠道传输。该技术可以捕捉胃肠道传输的细节，不涉及辐射，并且能够在患者进行日常生活的同时进行长时间记录。 在该项目的第一阶段，将在实验室构建并测试胃肠传输测量系统（GTMS）的原型。测试将集中于确定胶囊跟踪系统的准确性以及系统捕获瞬态运动的能力。在第二阶段，将对胃肠功能正常和异常的志愿者受试者进行临床示范测试。