RESEARCH TRAINING IN THE NEUROSCIENCES

神经科学的研究培训

• 批准号: 6363810
• 负责人: GERRY S OXFORD
• 金额: $ 29.7万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-30 至 2003-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6363810
• 关键词: RESEARCH; TRAINING; NEUROSCIENCES

Support is requested for a broad, comprehensive and fundamental interdisciplinary predoctoral training program in the neurosciences at the University of North Carolina at Chapel Hill. The proposed training program is intended to consolidate 2 existing training grants from the NIMH and NINDS. The training will be administered by the interdepartmental Curriculum in Neurobiology which is in its fourth decade of existence. Training will involve 53 faculty members of the Curriculum representing research laboratories in 14 departments or programs. These research facilities are well-equipped and funded for a wide variety of anatomical, molecular, genetic, chemical, electrophysiological, behavioral, and biophysical investigations. During the past year the Curriculum has become closely integrated with the new UNC Neuroscience Center providing expanded opportunities for training through the development of new research laboratories and the recruitment of new faculty. The formal training program is already in place and constitutes a series of required and elective learning activities leading to the Ph.D. in Neurobiology. Activities include formal coursework in a recently reorganized curriculum, laboratory apprenticeship research with individual faculty mentors, focused dissertation research, research seminars, techniques seminar, clinical correlation experiences, journal clubs and discussion groups on topics of career development and research integrity. In addition, an annual Carolina Neuroscience Symposium will expose trainees to current thought on specialized topics presented by distinguished scientists from outside UNC. The proposed training program will take advantage of several areas of particular strength in neurobiology research at UNC including: (1) recovery and regeneration following spinal neuron injury, (2) molecular correlations of specific sensory neuronal function, (3) response of the nervous system to toxic challenge, (4) structure, function, and regulation of neurotransmitter receptors and transporters, (5) mechanisms of signal transduction and ion channel function, (6) cell and molecular biology of synaptic transmission and synaptogenesis, (7) neuroendocrine and neuroimmune interactions, (8) functional imaging of nervous system activity in vitro, in vivo, and in situ, and (9) distribution and regulation of neuropeptides active in various regions of the central nervous system. Support is requested for 10 predoctoral trainees. Qualified minority candidates will be aggressively recruited.

支持广泛的，全面的和基本的跨学科的神经科学在北卡罗来纳州大学在查佩尔山的博士前培训计划的要求。拟议的培训方案旨在合并NIMH和NINDS现有的两项培训赠款。培训将由神经生物学跨部门课程管理，这是在其存在的第四个十年。培训将涉及53名教师的课程代表研究实验室在14个部门或计划。这些研究设施设备齐全，并为各种解剖学，分子，遗传学，化学，电生理学，行为学和生物物理学研究提供资金。在过去的一年中，课程已经与新的神经科学中心紧密结合，通过开发新的研究实验室和招聘新的教师来提供更多的培训机会。正式的培训计划已经到位，并构成了一系列必要的和选修的学习活动，导致博士学位。神经生物学活动包括在最近重新组织的课程，实验室学徒研究与个别教师导师，重点论文研究，研究研讨会，技术研讨会，临床相关经验，期刊俱乐部和讨论小组的职业发展和研究诚信的主题正式课程。此外，一年一度的卡罗莱纳神经科学研讨会将使学员了解来自美国以外的杰出科学家提出的专业主题的最新思想。拟议的培训计划将利用在神经生物学研究的几个领域的优势，包括：（1）脊髓神经元损伤后的恢复和再生，（2）特定感觉神经元功能的分子相关性，（3）神经系统对毒性攻击的反应，（4）神经递质受体和转运蛋白的结构、功能和调节，（5）信号转导和离子通道功能的机制，（6）突触传递和突触发生的细胞和分子生物学，（7）神经内分泌和神经免疫相互作用，（8）体外、体内和原位神经系统活动的功能成像，和（9）在中枢神经系统的各个区域中具有活性的神经肽的分布和调节。请求为10名博士前学员提供支助。将积极征聘合格的少数族裔候选人。